Basic Information

Symbol
AIRN
RNA class
lncRNA
Alias
AIR ENSG00000268257.2 IGF2R-AS1 IGF2RAS NCRNA00088
Location (GRCh38)
Forensic tag(s)
Other applications

Transcripts

ID Sequence Length GC content
AIRN:1 GAAAGCACACACCAUGCUGGAAAGGAGAGAGAAGGAAAAACCCACUCCU… 1489 nt 0.4097
AIRN:2 GAAAGCACACACCAUGCUGGAAAGGAGAGAGAAGGAAAAACCCACUCCU… 4374 nt 0.5176
Summary

Both spliced and un-spliced long non-coding RNAs are transcribed from this gene. This gene overlaps on the opposite strand the second intron of the insulin-like growth factor 2 receptor gene; a CpG island associated with the second intron denotes an active promoter that drives the expression of this gene. The related mouse gene is responsible for silencing the insulin-like growth factor 2 receptor gene and flanking genes in the imprinted gene cluster of mice. This gene may be expressed in Wilms tumors. [provided by RefSeq, Feb 2013]

Forensic Context

The provided literature, a consensus statement, notes that the AIRN is an antisense non-coding RNA involved in controlling parental imprinting in mice [Mattick et al. DOI:10.1038/s41580-022-00566-8].