Basic Information

Symbol
LINCMD1
RNA class
lncRNA
Alias
ENSG00000225613 ENSG00000225613.1 ENSG00000225613.2 MIR133BHG OTTHUMG00000014842.1 RP11-771D21.2
Location (GRCh38)
Forensic tag(s)
Mechanical injury analysis Wound age identification

Transcripts

ID Sequence Length GC content
LINCMD1:1 CCUUCCCCCACACCUUACUACUGCUUUGAACCAGUGUGCUGCAUUGAAA… 518 nt 0.4981
LINCMD1:2 AUGAGGAAACCCAGGCCUGGAGAGGUCAAGCAACUUGCUCAAGUGGCAC… 462 nt 0.5022
LINCMD1:3 AGCACCUUCAACUAAACUCCAUUCUGUGCUGCCCUUUGGAACACCCACU… 366 nt 0.4781
Summary

No relevant information is available at the moment.

Forensic Context

A study in mice and humans demonstrated that the LINCMD1 is a long noncoding RNA that acts as a competing endogenous RNA to sponge miR-133 and miR-135 away from MAML1 and MEF2C mRNAs, thereby regulating muscle differentiation, with its interaction with HuR fine-tuning miRNA levels [Flynn and Chang DOI:10.1016/j.stem.2014.05.014]. A study in mice demonstrated that the LINCMD1 was significantly upregulated on days 3, 6, and 12 following skeletal muscle contusion injury [Zheng et al. DOI:10.3892/etm.2019.7871].