Basic Information

Symbol
lnc-COX10-4
RNA class
lncRNA
Alias
AC005224.3 ENSG00000266378.1 OTTHUMG00000179687.1 RP11-214O1.3
Location (GRCh38)
17:14327335-14329474
UCSC Genome Browser Search in Marker Scope
Forensic tag(s)
Sudden cardiac death diagnosis Time since deposition estimation
External database
Ensembl LNCipedia RNAcentral

Transcripts

ID Sequence Length GC content
lnc-COX10-4:1 AUUUAUUAGUCUGAACAGAUGUUGAUUACUGGCCACCAGAGGUAAAGCA… 2140 nt 0.4042
Summary

No relevant information is available at the moment.

Forensic Context

A study in humans demonstrated that the deletion allele of the lnc-COX10-4 polymorphism (rs397763766) in the COX10 gene was significantly associated with increased susceptibility to sudden cardiac death (SCD) in a Chinese case-control population, with an odds ratio of 1.61 [Yang et al. DOI:10.1089/dna.2020.6086]. A study in human blood samples stored at 4°C demonstrated that the lnc-COX10-4 was one of 11 continuously upregulated transcripts identified as a potential time-marker for determining the time since deposition of bloodstains [Zhang et al. DOI:10.1016/j.forsciint.2024.111930].