Basic Information
Symbol
lnc-ELFN2-2
RNA class
lncRNA
Alias
ELFN2
ENSG00000243902.1
ENSG00000243902.2
ENSG00000243902.6
FP325335.1
OTTHUMG00000150561.1
RP1-63G5.5
Location (GRCh38)
22:37339583-37427470
Forensic tag(s)
Forensic psychiatry evaluation
Sudden unexpected death diagnosis
Drug abuse diagnoses
External database
Transcripts
| ID | Sequence | Length | GC content |
|---|---|---|---|
| lnc-ELFN2-2:10 | GUGCGCACGUGUUUGCGCAGAUGGAGACGAGGUUCCGCCGAGGCCCGUC… | 532 nt | 0.6335 |
| lnc-ELFN2-2:11 | AGUGAUAGUGCUUUUAAGAUGUUUAAAGUUGGCUCAGGAUUAAAUGAGU… | 1970 nt | 0.5756 |
| lnc-ELFN2-2:12 | ACACGCGCGCUCCCAGACACACACACAGACACACGCGGGCCACCCCACG… | 601 nt | 0.6206 |
| lnc-ELFN2-2:5 | CACACGCGCGCUCCCAGACACACACACAGACACACGCGGGCCACCCCAC… | 558 nt | 0.6505 |
| lnc-ELFN2-2:6 | ACAGACACACGCGGGCCACCCCACGGCCACGCACCCCGCACCCACACCC… | 577 nt | 0.6187 |
| lnc-ELFN2-2:7 | AGAGGCUCGAUGGUGGACGGUGUGCCAGCCGGUGCCACACUGCACCUCU… | 517 nt | 0.6151 |
| lnc-ELFN2-2:8 | GCUGUGCAUGUGAGCAGAGGCCAGAGGCGGAGGUGGAGAAGGAGAGGAC… | 481 nt | 0.6299 |
| lnc-ELFN2-2:9 | AGAGAAGCGGCGAAGAGGGCGGAGAGCAGAGAAGACGUCCUGGAGGAGG… | 579 nt | 0.6442 |
Summary
No relevant information is available at the moment.
Forensic Context
A review of postmortem human brain studies found that the lnc-ELFN2-2 is upregulated in the anterior cingulate cortex of subjects with major depressive disorder who died by suicide [Yoshino & Dwivedi DOI:10.3389/fpsyt.2020.543893]. A study in mice demonstrated that binge-like ethanol consumption via a drinking-in-the-dark paradigm significantly increased the lnc-ELFN2-2 expression in the prefrontal cortex, as identified by RNA-seq analysis [Vallerini et al. DOI:10.1016/J.Neuroscience.2020.09.010].