Basic Information
Symbol
DNM3OS
RNA class
lncRNA
Alias
DNM3-AS1
ENSG00000230630.1
ENSG00000230630.2
ENSG00000230630.3
ENSG00000230630.4
MIR199A2HG
OTTHUMG00000040855.2
Location (GRCh38)
1:172136531-172144835
Forensic tag(s)
Sudden cardiac death diagnosis
External database
Transcripts
| ID | Sequence | Length | GC content |
|---|---|---|---|
| DNM3OS:1 | CUUUUCCUGGUCCUAAAUUCAUUGCCAGUUCCCCAGUCUGCAGCAAAUG… | 7957 nt | 0.3349 |
| DNM3OS:2 | CUUUUCCUGGUCCUAAAUUCAUUGCCAGUUCCCCAGUCUGCAGCAAAUG… | 4051 nt | 0.3392 |
| DNM3OS:3 | CUUUUCCUGGUCCUAAAUUCAUUGCCAGUUCCCCAGUCUGCAGCAAAUG… | 6252 nt | 0.3370 |
| DNM3OS:4 | AGCAAAUGUGCCACGUCAAGACUGGAAAUCACAGCCCUUGAGUGUGUCU… | 568 nt | 0.4049 |
| DNM3OS:5 | AGCAAAUGUGCCACGUCAAGACUGGAAAUCACAGCCCUUGAGUGUGUCU… | 4358 nt | 0.3318 |
| DNM3OS:6 | GCAUCAUUCCUUUAAUUGAGCAGAGUUAACUGGAUCAAAUUAUUUAUGG… | 1538 nt | 0.2945 |
Summary
Enables miRNA inhibitor activity via base-pairing. Involved in cellular response to transforming growth factor beta stimulus and regulation of macromolecule metabolic process. Predicted to be part of RISC complex. [provided by Alliance of Genome Resources, Jul 2025]
Forensic Context
A study in mice demonstrated that the long non-coding RNA Dnm3os was significantly upregulated in cardiac tissues following ischemia-reperfusion injury and in hypoxic HL-1 cells, identifying it as one of the top differentially expressed transcripts in this pathological context [Luo et al. DOI:10.3389/fcell.2021.615950].