Basic Information

Symbol
lnc-METTL15-10
RNA class
lncRNA
Alias
BDNF-AS
Location (GRCh38)
11:27695459-27695686
UCSC Genome Browser Search in Marker Scope
Forensic tag(s)
Forensic psychiatry-related diagnoses Mechanical injury analysis
External database
HGNC NCBI Ensembl OMIM LNCipedia RNAcentral

Transcripts

ID Sequence Length GC content
lnc-METTL15-10:1 AGGCAUGUCAAAAACACAGAGGGUCGUCAUAAAGUUUCCGUCAGACCAA… 228 nt 0.3860
Summary

No relevant information is available at the moment.

Forensic Context

The long non-coding RNA BDNF-AS is identified as a therapeutic target in Alzheimer's disease and schizophrenia, where it targets BDNF, GDNF, and EPHB2 [Das et al. DOI:10.1080/21655979.2021.2003667]. A study in rats and mice demonstrated that the lnc-METTL15-10 mRNA levels increased after cortical impact injury, with protein levels elevated primarily in microglia in the hippocampus post-TBI, suggesting a neuroprotective role [Dash et al. DOI:10.23/B:NERE.0000023614.30084.eb].