Basic Information
Symbol
lnc-METTL22-2
RNA class
lncRNA
Alias
LINC02152
AC018767.3
ENSG00000260058.1
OTTHUMG00000176685.1
RP11-279O17.3
XLOC_011636
linc-C16orf68-1
Location (GRCh38)
16:8295915-8357860
Forensic tag(s)
Forensic psychiatry evaluation
Cause of death analysis
External database
Transcripts
| ID | Sequence | Length | GC content |
|---|---|---|---|
| lnc-METTL22-2:1 | UUUCUCUGUUGGAGUGCCUUCAUUUACAAAGCAUAUUUUUCAAGUCUUU… | 1028 nt | 0.4864 |
| lnc-METTL22-2:2 | CAGCCAUCAGGCAACCUGGGCAUUGUGGAGGCUUCUCAAAGUAGAGAGG… | 768 nt | 0.5026 |
| lnc-METTL22-2:3 | UCUAACCUGAGAACCUAUUACCACCACCCAGUGUCCUCAGAAGUCAUGA… | 481 nt | 0.4782 |
| lnc-METTL22-2:4 | UUUUCUCUGUUGGAGUGCCUUCAUUUACAAAGCAUAUUUUUCAAGUCUU… | 1005 nt | 0.4846 |
Summary
No relevant information is available at the moment.
Forensic Context
A study in humans demonstrated that the lnc-METTL22-2 is down-regulated in peripheral blood mononuclear cells of patients with major depressive disorder and its expression shows a significant negative association with suicide risk, being markedly lower in patients with suicidal ideation and past suicide attempts compared to controls [Cui et al. DOI:10.1002/brb3.711]. A forensic review further identifies the lnc-METTL22-2 as a biomarker of suicidal ideation in MDD patients, supporting its potential application in cause-of-death analysis [Song et al. DOI:10.1007/s00414-023-03091-1].