Basic Information

Symbol
lnc-RNASEH2B-4
RNA class
lncRNA
Alias
DLEU1
Location (GRCh38)
13:50713618-50715340
UCSC Genome Browser Search in Marker Scope
Forensic tag(s)
Sudden cardiac death diagnosis Other applications
External database
HGNC NCBI Ensembl OMIM UniProt LNCipedia RNAcentral

Transcripts

ID Sequence Length GC content
lnc-RNASEH2B-4:1 GACAGGAAAGGGGUUCUAUCCAUGAUCUUACAAUUCCUAAACAGCAACA… 1723 nt 0.4689
Summary

No relevant information is available at the moment.

Forensic Context

A study in human patients identified DLEU1 as the most up-regulated long non-coding RNA in acute myocardial infarction (AMI) through RNA sequencing of peripheral blood samples, a finding supported by subsequent qRT-PCR validation [Wang et al. DOI:10.2147/IJGM.S329391]. A study in cultured human aortic endothelial cells demonstrated that the lnc-RNASEH2B-4 was identified as a radiation-responsive long non-coding RNA, serving as a '0 Gy marker' that could differentiate unirradiated samples from those exposed to X-ray doses of 1-10 Gy at the 24-hour post-radiation time point [Chopra et al. DOI:10.1038/s41598-022-24051-6].