Basic Information
Symbol
lnc-SRSF6-1
RNA class
lncRNA
Alias
PTPRT-DT
AL021395.1
ENSG00000233508.1
ENSG00000233508.2
OTTHUMG00000032498.1
RP1-269M15.3
Location (GRCh38)
20:43190065-43202995
Forensic tag(s)
Cause of death analysis
Forensic psychiatry evaluation
External database
Transcripts
| ID | Sequence | Length | GC content |
|---|---|---|---|
| lnc-SRSF6-1:1 | CAAGCAUCGUCUGCCCUGUGGGGGCGCAGCUCCUGGACUUUUUAAAAUU… | 805 nt | 0.4547 |
| lnc-SRSF6-1:2 | CGACCAGCUCGGGCCGCUGGCACAGUCACGCGCGUCCACACAUCACCCC… | 2131 nt | 0.4463 |
| lnc-SRSF6-1:3 | CACCCUCUCCGGGGCCGACCAGCUCGGGCCGCUGGCACAGUCACGCGCG… | 2232 nt | 0.4521 |
| lnc-SRSF6-1:4 | ACACGCCCGCGGCUGGCACACGCGGGCUCCCCCGCGCACCCUCUCCGGG… | 962 nt | 0.5094 |
| lnc-SRSF6-1:5 | ACACGCCCGCGGCUGGCACACGCGGGCUCCCCCGCGCACCCUCUCCGGG… | 3868 nt | 0.4723 |
Summary
No relevant information is available at the moment.
Forensic Context
A review of human postmortem brain studies found that the lnc-SRSF6-1 is upregulated in the anterior cingulate cortex of subjects with major depressive disorder who died by suicide and is correlated with PTPRT [Yoshino & Dwivedi DOI:10.3389/fpsyt.2020.543893], and a separate forensic review identified it as differentially expressed in the brains of depressed patients who died by suicide, indicating its potential as a biomarker for cause-of-death analysis related to suicide [Song et al. DOI:10.1007/s00414-023-03091-1].