Basic Information
Symbol
FENDRR
RNA class
lncRNA
Alias
AC009108.1
ENSG00000246979
ENSG00000268388.1
ENSG00000268388.5
XLOC_012046
linc-COX4NB-9
lincFOXF1
onco-lncRNA-21
Location (GRCh38)
16:86473638-86509099
Forensic tag(s)
-
Transcripts
| ID | Sequence | Length | GC content |
|---|---|---|---|
| FENDRR:1 | AUUUGGCCCCGCGGCCCCGUUUUCAAAGCGCAGGUUCCGAUUUCCCGAG… | 2843 nt | 0.5244 |
| FENDRR:10 | CGGGUAUCAGGAUCAUACUCAAACCCCAACCCCUGCCCGCCCCAGCCAG… | 2568 nt | 0.5019 |
| FENDRR:11 | CGGGUAUCAGGAUCAUACUCAAACCCCAACCCCUGCCCGCCCCAGCCAG… | 3300 nt | 0.4473 |
| FENDRR:12 | GACGGUUGGGAGUGGGAGGCCUCGGCGCUGUUCUCUGGAUGCAACUGAG… | 3379 nt | 0.4845 |
| FENDRR:13 | UAGAUGGGAUUUACAUCUGAAAAACCAAGUGAGAAACUGAAGACCAGAG… | 355 nt | 0.4451 |
| FENDRR:14 | GAUGGGAUUUACAUCUGAAAAACCAAGUGAGAAACUGAAGACCAGAGAG… | 2823 nt | 0.4881 |
| FENDRR:15 | GAUGGGAUUUACAUCUGAAAAACCAAGUGAGAAACUGAAGACCAGAGAG… | 2825 nt | 0.4878 |
| FENDRR:16 | GAUGGGAUUUACAUCUGAAAAACCAAGUGAGAAACUGAAGACCAGAGAG… | 2835 nt | 0.4878 |
| FENDRR:17 | CGACACAGUGAUGGUAUCUUGCAGCUGCUGCUUCUGUCCAAGGCACUGC… | 2138 nt | 0.4654 |
| FENDRR:18 | ACUGCGCGCCAGGCCAGGUUCCUGAGAGCAGACAGCGCGGGCUGGGAGC… | 563 nt | 0.5755 |
Showing 1 to 10 of 30 entries
Summary
This gene produces a spliced long non-coding RNA transcribed bidirectionally with FOXF1 on the opposite strand. A similar gene in mouse is essential for normal development of the heart and body wall. The encoded transcript is thought to act by binding to polycomb repressive complex 2 (PRC2) and/or TrxG/MLL complexes to promote the methylation of the promoters of target genes, thus reducing their expression. It has been suggested that this transcript may play a role in the progression of gastric cancer. Alternatively spliced transcript variants have been identified. [provided by RefSeq, Mar 2015]
Forensic Context
No relevant information is available at the moment.