Basic Information

Symbol
FENDRR
RNA class
lncRNA
Alias
AC009108.1 ENSG00000246979 ENSG00000268388.1 ENSG00000268388.5 XLOC_012046 linc-COX4NB-9 lincFOXF1 onco-lncRNA-21
Location (GRCh38)
Forensic tag(s)
-

Transcripts

ID Sequence Length GC content
FENDRR:19 ACUGCGCGCCAGGCCAGGUUCCUGAGAGCAGACAGCGCGGGCUGGGAGC… 969 nt 0.5212
FENDRR:2 CAGGCCAGGUUCCUGAGAGCAGACAGCGCGGGCUGGGAGCGCCGGCAAG… 960 nt 0.5188
FENDRR:20 ACUGCGCGCCAGGCCAGGUUCCUGAGAGCAGACAGCGCGGGCUGGGAGC… 3121 nt 0.4681
FENDRR:21 ACUGCGCGCCAGGCCAGGUUCCUGAGAGCAGACAGCGCGGGCUGGGAGC… 3211 nt 0.4671
FENDRR:22 ACUGCGCGCCAGGCCAGGUUCCUGAGAGCAGACAGCGCGGGCUGGGAGC… 3606 nt 0.4634
FENDRR:23 ACUGCGCGCCAGGCCAGGUUCCUGAGAGCAGACAGCGCGGGCUGGGAGC… 731 nt 0.5499
FENDRR:24 ACUGCGCGCCAGGCCAGGUUCCUGAGAGCAGACAGCGCGGGCUGGGAGC… 2630 nt 0.5198
FENDRR:25 AUACUCAAACCCCAACCCCUGCCCGCCCCAGCCAGGAGGGGAGACGGUU… 4093 nt 0.4432
FENDRR:26 AUACUCAAACCCCAACCCCUGCCCGCCCCAGCCAGGAGGGGAGACGGUU… 3164 nt 0.4520
FENDRR:27 AUACUCAAACCCCAACCCCUGCCCGCCCCAGCCAGGAGGGGAGACGGUU… 609 nt 0.4943
Showing 11 to 20 of 30 entries
Summary

This gene produces a spliced long non-coding RNA transcribed bidirectionally with FOXF1 on the opposite strand. A similar gene in mouse is essential for normal development of the heart and body wall. The encoded transcript is thought to act by binding to polycomb repressive complex 2 (PRC2) and/or TrxG/MLL complexes to promote the methylation of the promoters of target genes, thus reducing their expression. It has been suggested that this transcript may play a role in the progression of gastric cancer. Alternatively spliced transcript variants have been identified. [provided by RefSeq, Mar 2015]

Forensic Context

No relevant information is available at the moment.