Basic Information
Symbol
FENDRR
RNA class
lncRNA
Alias
AC009108.1
ENSG00000246979
ENSG00000268388.1
ENSG00000268388.5
XLOC_012046
linc-COX4NB-9
lincFOXF1
onco-lncRNA-21
Location (GRCh38)
16:86473638-86509099
Forensic tag(s)
-
Transcripts
| ID | Sequence | Length | GC content |
|---|---|---|---|
| FENDRR:28 | AUACUCAAACCCCAACCCCUGCCCGCCCCAGCCAGGAGGGGAGACGGUU… | 863 nt | 0.4925 |
| FENDRR:29 | AUACUCAAACCCCAACCCCUGCCCGCCCCAGCCAGGAGGGGAGACGGUU… | 569 nt | 0.4868 |
| FENDRR:3 | AGGCCAGGUUCCUGAGAGCAGACAGCGCGGGCUGGGAGCGCCGGCAAGG… | 553 nt | 0.5714 |
| FENDRR:30 | AGCAGACAGCGCGGGCUGGGAGCGCCGGCAAGGGCGGCCCUCGCGCACC… | 2678 nt | 0.5116 |
| FENDRR:4 | AGCAGACAGCGCGGGCUGGGAGCGCCGGCAAGGGCGGCCCUCGCGCACC… | 3095 nt | 0.4662 |
| FENDRR:5 | AGCAGACAGCGCGGGCUGGGAGCGCCGGCAAGGGCGGCCCUCGCGCACC… | 3099 nt | 0.4660 |
| FENDRR:6 | AGCAGACAGCGCGGGCUGGGAGCGCCGGCAAGGGCGGCCCUCGCGCACC… | 2676 nt | 0.5120 |
| FENDRR:7 | CGGCAAGGGCGGCCCUCGCGCACCUGGCUGCCAGCCCGCAGGGGGCUCG… | 2579 nt | 0.5157 |
| FENDRR:8 | GAGAGCGGAGCGCAGGACAGCGCAGGAGCCCCGGCGCAUCGCGGCGCGC… | 546 nt | 0.5238 |
| FENDRR:9 | GGUAAAACUGCCCAGGCCCCGGGUAUCAGGAUCAUACUCAAACCCCAAC… | 602 nt | 0.4934 |
Showing 21 to 30 of 30 entries
Summary
This gene produces a spliced long non-coding RNA transcribed bidirectionally with FOXF1 on the opposite strand. A similar gene in mouse is essential for normal development of the heart and body wall. The encoded transcript is thought to act by binding to polycomb repressive complex 2 (PRC2) and/or TrxG/MLL complexes to promote the methylation of the promoters of target genes, thus reducing their expression. It has been suggested that this transcript may play a role in the progression of gastric cancer. Alternatively spliced transcript variants have been identified. [provided by RefSeq, Mar 2015]
Forensic Context
No relevant information is available at the moment.