Basic Information
Symbol
MAGI1-IT1
RNA class
lncRNA
Alias
ENSG00000240256.1
ENSG00000272610.1
OTTHUMG00000158737.1
Location (GRCh38)
3:65872815-65954558
Forensic tag(s)
Sudden cardiac death diagnosis
External database
Transcripts
| ID | Sequence | Length | GC content |
|---|---|---|---|
| MAGI1-IT1:1 | CUUUGUAAUUUGUAGCAACAAACCUGGGGUCAGACACUCCACUGCCUGU… | 2567 nt | 0.4231 |
| MAGI1-IT1:2 | GUAAUUUGUAGCAACAAACCUGGGGUCAGACACUCCACUGCCUGUGCAU… | 2786 nt | 0.4253 |
| MAGI1-IT1:3 | GUAAUUUGUAGCAACAAACCUGGGGUCAGACACUCCACUGCCUGUGCAU… | 2563 nt | 0.4233 |
Summary
No relevant information is available at the moment.
Forensic Context
A review of long noncoding RNAs in cardiovascular diseases noted that the MAGI1-IT1 is a protective long noncoding RNA against cardiac hypertrophy, functioning as a competing endogenous RNA that sponges miR-302e to derepress DKK1 and inactivate Wnt/beta-catenin signaling [Chih-Fan Yeh et al. DOI:10.1186/s12929-020-00647-w].