Basic Information
Symbol
MIR4453HG
RNA class
lncRNA
Alias
DKFZP434I0714
ENSG00000268471.3
ENSG00000268471.4
ENSG00000268471.5
ENSG00000268471.6
LINC02486
MIR4453
Location (GRCh38)
4:152535193-152546747
Forensic tag(s)
Sudden cardiac death diagnosis
External database
Transcripts
| ID | Sequence | Length | GC content |
|---|---|---|---|
| MIR4453HG:10 | GGGACAGUCAGGUUUGGGAGACUCCGGAUUUUGUUUUUGUAAAGUUUCC… | 4051 nt | 0.5127 |
| MIR4453HG:11 | GAAGUGGGGAUCGGCGAGCGGGUGGGUGCGCCUCGGGCCGCGGGACUCG… | 3000 nt | 0.4357 |
| MIR4453HG:12 | GAAGUGGGGAUCGGCGAGCGGGUGGGUGCGCCUCGGGCCGCGGGACUCG… | 2997 nt | 0.4358 |
| MIR4453HG:13 | CGGCGAGCGGGUGGGUGCGCCUCGGGCCGCGGGACUCGCAGCCGCCACC… | 2988 nt | 0.4354 |
| MIR4453HG:14 | GCCUCGGGCCGCGGGACUCGCAGCCGCCACCGCCGCUGCCGCCUCUACG… | 2968 nt | 0.4330 |
| MIR4453HG:15 | GCCUCGGGCCGCGGGACUCGCAGCCGCCACCGCCGCUGCCGCCUCUACG… | 2971 nt | 0.4329 |
| MIR4453HG:16 | GCCUCGGGCCGCGGGACUCGCAGCCGCCACCGCCGCUGCCGCCUCUACG… | 5385 nt | 0.4227 |
| MIR4453HG:17 | GAGUCGAGCCUAAGCUGCCGCCCGAUCUUACCCCUGACCCGAGGGCGGC… | 10370 nt | 0.4482 |
Summary
No relevant information is available at the moment.
Forensic Context
The long noncoding RNA DKFZP434I0714 is identified as a biomarker for predicting adverse cardiovascular events in uremic patients, as it modulates stress-induced endothelial cell apoptosis, endothelial dysfunction, and vascular inflammation [Chih-Fan Yeh et al. DOI:10.1186/s12929-020-00647-w].