Basic Information

Symbol
NORAD
RNA class
lncRNA
Alias
ENSG00000260032.1 LINC00657 OTTHUMG00000175580.1 RP4-550H1.6
Location (GRCh38)
20:36045299-36051016
UCSC Genome Browser Search in Marker Scope
Forensic tag(s)
Wound age identification
External database
HGNC NCBI Ensembl OMIM LNCipedia RNAcentral

Transcripts

ID Sequence Length GC content
NORAD:1 CGCAAGGGCACUUCCGGUACCGCUCCUCUCUUGCCAGCGCAGAGAACUG… 5373 nt 0.4184
NORAD:10 AGAGAUCGCGGAGAGACGCAGAACGCAGCCCGCUCCUCCAGGGCCCUCC… 3123 nt 0.4448
NORAD:2 GAGAACUGCCAAGUCAGUUCCGGUCCGGCAGAGAUCGCGGAGAGACGCA… 4266 nt 0.4398
NORAD:3 AGUUCCGGUCCGGCAGAGAUCGCGGAGAGACGCAGAACGCAGCCCGCUC… 5339 nt 0.4156
NORAD:4 AGUUCCGGUCCGGCAGAGAUCGCGGAGAGACGCAGAACGCAGCCCGCUC… 5343 nt 0.4153
NORAD:5 AGUUCCGGUCCGGCAGAGAUCGCGGAGAGACGCAGAACGCAGCCCGCUC… 2205 nt 0.4612
NORAD:6 UCUAGUCUUUCUAGGUGUUUAAAAGUGUACAACGGCCUGUCGCAGUGGC… 666 nt 0.4970
NORAD:7 GUAUGCAGGGAGAGGGGUUCUGUGCUCCUGAGAUUAGUUCAGAUGGUCU… 1207 nt 0.3579
NORAD:8 AGAGAUCGCGGAGAGACGCAGAACGCAGCCCGCUCCUCCAGGGCCCUCC… 5289 nt 0.4126
NORAD:9 AGAGAUCGCGGAGAGACGCAGAACGCAGCCCGCUCCUCCAGGGCCCUCC… 5325 nt 0.4148
Summary

Predicted to enable protein sequestering activity. Predicted to be involved in several processes, including determination of adult lifespan; hair follicle development; and skeletal muscle fiber development. Predicted to be active in cytoplasm. Biomarker of lung non-small cell carcinoma. [provided by Alliance of Genome Resources, Jul 2025]

Forensic Context

The long non-coding RNA NORAD (non-coding RNA activated by DNA damage) is induced by DNA damage and functions to maintain genome stability by sequestering Pumilio proteins into phase-separated domains, thereby preventing aberrant mitosis [Mattick et al. DOI:10.1038/s41580-022-00566-8]. A study in human endothelial cells demonstrated that the NORAD is activated by hypoxia, a key condition in wound healing, which supports its investigation for forensic injury time estimation [Li et al. DOI:10.1093/fsr/owad003].