Basic Information

Symbol
OIP5-AS1
RNA class
lncRNA
Alias
AC012652.1 ENSG00000247556 ENSG00000247556.2 ENSG00000247556.6 OTTHUMG00000172547.2 XLOC_011226 cyrano linc-NUSAP1 linc-OIP5
Location (GRCh38)
15:41283963-41508868
UCSC Genome Browser Search in Marker Scope
Forensic tag(s)
Cause of death analysis Sudden death from respiratory system disease
External database
HGNC NCBI Ensembl LNCipedia RNAcentral

Transcripts

ID Sequence Length GC content
OIP5-AS1:19 GCGUGCCGCUGCAAACUGGCCUCUGGGCCGGGGGCGAGCAGCCCCCGGG… 1350 nt 0.4044
OIP5-AS1:2 GUGGGAACGGCCCACCGCAGGGUUGGCCACCUUGAGAAGCUGCGAAGAU… 263 nt 0.5894
OIP5-AS1:20 GCGUGCCGCUGCAAACUGGCCUCUGGGCCGGGGGCGAGCAGCCCCCGGG… 1384 nt 0.4053
OIP5-AS1:21 UCUGUUUGAGUAAUAUUGUAUACUAAAAUUACUAGCACCAGUGAGGGCC… 8656 nt 0.3782
OIP5-AS1:22 CACAGGAAGAAAAUUUUCCUUGACCUUUAGGUGCUUUUAUAUUCAUCUC… 5283 nt 0.3737
OIP5-AS1:23 GAAAAUUUUCCUUGACCUUUAGGUGCUUUUAUAUUCAUCUCAAAAACAA… 8568 nt 0.3786
OIP5-AS1:24 CUUGAACUCCGGACCUGGUGAUCCACCCACUUCGGCUUCCCGAAGUGCU… 8550 nt 0.3805
OIP5-AS1:25 UCCCAGCUACUCAGGAGGCUGAGGCAGUAGAAUCACUUAAACCUGAGAG… 4157 nt 0.3676
OIP5-AS1:26 AAGCUGCGAAGAUGGCGGAGUAAGGCGUGCCGCUGCAAACUGGCCUCUG… 568 nt 0.5229
OIP5-AS1:27 AAGCUGCGAAGAUGGCGGAGUAAGGCGUGCCGCUGCAAACUGGCCUCUG… 658 nt 0.4210
Showing 11 to 20 of 36 entries
Summary

This is a conserved gene that produces a long non-coding RNA that maintains cell proliferation in embryonic stem cells. This RNA can bind to and negatively regulate the activity of multiple cellular RNAs and microRNAs, including cyclin G associated kinase and ELAV like RNA binding protein 1. [provided by RefSeq, Dec 2017]

Forensic Context

A study in humans identified the OIP5-AS1 as a hub long non-coding RNA within a constructed ceRNA network for sepsis, having the highest degree distribution and being part of regulator pairs used for drug prediction [Wang et al. DOI:10.1016/j.heliyon.2024.e27379]. In a separate investigation of sepsis-induced acute respiratory distress syndrome, the OIP5-AS1 was noted as a potential regulator that modulates GPR65 expression through specific miRNAs and worsens LPS-induced acute lung injury/ARDS [Liu et al. DOI:10.3389/fimmu.2025.1528769].