Basic Information
Symbol
PCGEM1
RNA class
lncRNA
Alias
ENSG00000227418.1
ENSG00000227418.2
ENSG00000227418.6
LINC00071
NCRNA00071
OTTHUMG00000154342.1
PCAT9
Location (GRCh38)
2:192749718-192783952
Forensic tag(s)
Other applications
Transcripts
| ID | Sequence | Length | GC content |
|---|---|---|---|
| PCGEM1:1 | CAUGUAUUAAGUAGUAAGCUCCCAUGUUAACAGUUGUAACUUGCCUGGU… | 448 nt | 0.4219 |
| PCGEM1:2 | AAGGCACUCUGGCACCCAGUUUUGGAACUGCAGUUUUAAAAGUCAUAAA… | 1590 nt | 0.3465 |
| PCGEM1:3 | AAUUAGGCAGCAACCUUUUUGCCCUAUGCCGUAACCUGUGUCUGCAACU… | 759 nt | 0.4282 |
| PCGEM1:4 | AAUUCAUGGUAGUGCCCCAAGGCACUCUGGCACCCAGUUUUGGAACUGC… | 1608 nt | 0.3483 |
| PCGEM1:5 | AAUUCAUGGUAGUGCCCCAAGGCACUCUGGCACCCAGUUUUGGAACUGC… | 9549 nt | 0.3617 |
| PCGEM1:6 | AAGGCACUCUGGCACCCAGUUUUGGAACUGCAGUUUUAAAAGUCAUAAA… | 1590 nt | 0.3465 |
| PCGEM1:7 | GGCUGCAUUUACACCAAAACCAUGAAGGUGGCCCAAGUCAUCACUGAGA… | 335 nt | 0.4537 |
Summary
This gene produces a long non-coding RNA that is overexpressed in prostate cancer and may act a marker for tumor progression. This RNA may act a negative regulator of apoptosis, and may promote activity of androgen receptor and Myc. [provided by RefSeq, Dec 2017]
Forensic Context
A study in human postmortem nucleus accumbens tissue identified several long non-coding RNAs (lncRNAs) represented on Affymetrix microarrays, with five consistently detected; the abundance of the PCGEM1 was not consistently detected in the human nucleus accumbens samples in this investigation [Michelhaugh et al. DOI:10.1111/J.1471-4159.2010.07126.X].