Basic Information
Symbol
SOX2-OT
RNA class
lncRNA
Alias
DKFZp761J1324
ENSG00000242808
ENSG00000242808.1
ENSG00000242808.3
ENSG00000242808.7
ENSG00000242808.8
ENSG00000243341
ENSG00000243341.1
NCRNA00043
OTTHUMG00000158186.2
OTTHUMG00000158221.1
RP11-436A20.3
RP11-4B14.2
Location (GRCh38)
3:180989762-181836880
Forensic tag(s)
Forensic psychiatry evaluation
Drug abuse diagnoses
Transcripts
| ID | Sequence | Length | GC content |
|---|---|---|---|
| SOX2-OT:10 | AUUUGCUUUCAGCCGCAGAGAGAAGAAGCUGCCCAAGAAUGGAAAGGAA… | 609 nt | 0.4466 |
| SOX2-OT:100 | ACUGGAGGAAAGGGCAAGGGAUUGCAGUGGCAAAGCUAGGCUAGGUCUU… | 1500 nt | 0.3947 |
| SOX2-OT:101 | GGGGAGAGUAAAGCCUCAUUUUUUUUUCAGUCACUCUAUCUGGGGUUGC… | 2011 nt | 0.3948 |
| SOX2-OT:102 | AUACAAGAGAGAACAAAAUGGUUAUUCAGGGGAACGCUUUCGAUUUUUA… | 1948 nt | 0.4004 |
| SOX2-OT:103 | GGGAUUGCAGUGGCAAAGCUAGGCUAGGUCUUGGAGGCUGGUGUAAGGC… | 607 nt | 0.5058 |
| SOX2-OT:104 | GGGAUUGCAGUGGCAAAGCUAGGCUAGGUCUUGGAGGCUGGUGUAAGGC… | 626 nt | 0.4936 |
| SOX2-OT:105 | GGGAUUGCAGUGGCAAAGCUAGGCUAGGUCUUGGAGGCUGGUGUAAGGC… | 753 nt | 0.4874 |
| SOX2-OT:106 | GGGAUUGCAGUGGCAAAGCUAGGCUAGGUCUUGGAGGCUGGUGUAAGGC… | 690 nt | 0.4681 |
| SOX2-OT:107 | GGGAUUGCAGUGGCAAAGCUAGGCUAGGUCUUGGAGGCUGGUGUAAGGC… | 873 nt | 0.4731 |
| SOX2-OT:108 | GGGAUUGCAGUGGCAAAGCUAGGCUAGGUCUUGGAGGCUGGUGUAAGGC… | 469 nt | 0.5139 |
Showing 1 to 10 of 127 entries
Summary
This gene produces alternatively spliced long non-coding RNAs. These RNAs were observed to be upregulated in tumor cells and positively correlated to expression of the SRY-box 2 gene. Overexpression of these transcripts may promote cell proliferation. [provided by RefSeq, Dec 2017]
Forensic Context
A study in human postmortem brain tissue identified the long noncoding RNA SOX2-OT as being upregulated in the dorsolateral prefrontal cortex of subjects with opioid use disorder compared to non-psychiatric controls [Mendez et al. DOI:10.1038/s41380-021-01259-y].