Basic Information
Symbol
SOX2-OT
RNA class
lncRNA
Alias
DKFZp761J1324
ENSG00000242808
ENSG00000242808.1
ENSG00000242808.3
ENSG00000242808.7
ENSG00000242808.8
ENSG00000243341
ENSG00000243341.1
NCRNA00043
OTTHUMG00000158186.2
OTTHUMG00000158221.1
RP11-436A20.3
RP11-4B14.2
Location (GRCh38)
3:180989762-181836880
Forensic tag(s)
Forensic psychiatry evaluation
Drug abuse diagnoses
Transcripts
| ID | Sequence | Length | GC content |
|---|---|---|---|
| SOX2-OT:66 | CAAUCAAACUGCUACAAGACAACACCCUGAUCUGGCAUGGACAUUCUCA… | 468 nt | 0.3782 |
| SOX2-OT:67 | AAAGACACGCUAUUUAAAUACAGAUCCAACUUAGAAAUAAUGUUUCAUU… | 692 nt | 0.3642 |
| SOX2-OT:68 | GUUGGAGUGCAGUGGCGCGAUCUUGGCUCACUGCAACCGCCACUUCCCA… | 540 nt | 0.4222 |
| SOX2-OT:69 | GGAAAACUGUCGUAAAAGGGGACGCGGAGGAGAAGGAAAGUCGCUCAAG… | 796 nt | 0.4246 |
| SOX2-OT:7 | AAUGCAUUUGCUUUCAGCCGCAGAGAGAAGAAGCUGCCCAAGAAUGGAA… | 1239 nt | 0.4350 |
| SOX2-OT:70 | GUAAAAGGGGACGCGGAGGAGAAGGAAAGUCGCUCAAGCAGUGGACAGA… | 1622 nt | 0.3200 |
| SOX2-OT:71 | GUAAAAGGGGACGCGGAGGAGAAGGAAAGUCGCUCAAGCAGUGGACAGA… | 1242 nt | 0.3422 |
| SOX2-OT:72 | GUAAAAGGGGACGCGGAGGAGAAGGAAAGUCGCUCAAGCAGUGGACAGA… | 1199 nt | 0.3420 |
| SOX2-OT:73 | GUAAAAGGGGACGCGGAGGAGAAGGAAAGUCGCUCAAGCAGUGGACAGA… | 1238 nt | 0.4055 |
| SOX2-OT:74 | AAAAGGGGACGCGGAGGAGAAGGAAAGUCGCUCAAGCAGUGGACAGAGC… | 3274 nt | 0.3745 |
Showing 91 to 100 of 127 entries
Summary
This gene produces alternatively spliced long non-coding RNAs. These RNAs were observed to be upregulated in tumor cells and positively correlated to expression of the SRY-box 2 gene. Overexpression of these transcripts may promote cell proliferation. [provided by RefSeq, Dec 2017]
Forensic Context
A study in human postmortem brain tissue identified the long noncoding RNA SOX2-OT as being upregulated in the dorsolateral prefrontal cortex of subjects with opioid use disorder compared to non-psychiatric controls [Mendez et al. DOI:10.1038/s41380-021-01259-y].