Basic Information
Symbol
SOX2-OT
RNA class
lncRNA
Alias
DKFZp761J1324
ENSG00000242808
ENSG00000242808.1
ENSG00000242808.3
ENSG00000242808.7
ENSG00000242808.8
ENSG00000243341
ENSG00000243341.1
NCRNA00043
OTTHUMG00000158186.2
OTTHUMG00000158221.1
RP11-436A20.3
RP11-4B14.2
Location (GRCh38)
3:180989762-181836880
Forensic tag(s)
Forensic psychiatry evaluation
Drug abuse diagnoses
Transcripts
| ID | Sequence | Length | GC content |
|---|---|---|---|
| SOX2-OT:75 | GGGGACGCGGAGGAGAAGGAAAGUCGCUCAAGCAGUGGACAGAGCGGAG… | 2151 nt | 0.4142 |
| SOX2-OT:76 | GGGGACGCGGAGGAGAAGGAAAGUCGCUCAAGCAGUGGACAGAGCGGAG… | 2291 nt | 0.4011 |
| SOX2-OT:77 | GGAGGAGAAGGAAAGUCGCUCAAGCAGUGGACAGAGCGGAGAAAGCGAC… | 1468 nt | 0.3610 |
| SOX2-OT:78 | GGAGAAGGAAAGUCGCUCAAGCAGUGGACAGAGCGGAGAAAGCGACUUC… | 2779 nt | 0.3591 |
| SOX2-OT:79 | GGAGAAGGAAAGUCGCUCAAGCAGUGGACAGAGCGGAGAAAGCGACUUC… | 392 nt | 0.4413 |
| SOX2-OT:8 | AAUGCAUUUGCUUUCAGCCGCAGAGAGAAGAAGCUGCCCAAGAAUGGAA… | 3547 nt | 0.3730 |
| SOX2-OT:80 | GGAGAAGGAAAGUCGCUCAAGCAGUGGACAGAGCGGAGAAAGCGACUUC… | 1390 nt | 0.3842 |
| SOX2-OT:81 | GGAGAAGGAAAGUCGCUCAAGCAGUGGACAGAGCGGAGAAAGCGACUUC… | 1080 nt | 0.4046 |
| SOX2-OT:82 | GAAGGAAAGUCGCUCAAGCAGUGGACAGAGCGGAGAAAGCGACUUCGGG… | 2207 nt | 0.4105 |
| SOX2-OT:83 | GACAGAGCGGAGAAAGCGACUUCGGUGAAUGAAGGAGGGAAGAAAGGAG… | 1766 nt | 0.3613 |
Showing 101 to 110 of 127 entries
Summary
This gene produces alternatively spliced long non-coding RNAs. These RNAs were observed to be upregulated in tumor cells and positively correlated to expression of the SRY-box 2 gene. Overexpression of these transcripts may promote cell proliferation. [provided by RefSeq, Dec 2017]
Forensic Context
A study in human postmortem brain tissue identified the long noncoding RNA SOX2-OT as being upregulated in the dorsolateral prefrontal cortex of subjects with opioid use disorder compared to non-psychiatric controls [Mendez et al. DOI:10.1038/s41380-021-01259-y].