Basic Information
Symbol
SOX2-OT
RNA class
lncRNA
Alias
DKFZp761J1324
ENSG00000242808
ENSG00000242808.1
ENSG00000242808.3
ENSG00000242808.7
ENSG00000242808.8
ENSG00000243341
ENSG00000243341.1
NCRNA00043
OTTHUMG00000158186.2
OTTHUMG00000158221.1
RP11-436A20.3
RP11-4B14.2
Location (GRCh38)
3:180989762-181836880
Forensic tag(s)
Forensic psychiatry evaluation
Drug abuse diagnoses
Transcripts
| ID | Sequence | Length | GC content |
|---|---|---|---|
| SOX2-OT:84 | AAUGCAUUUGCUUUCAGCCGCAGAGAGAAGAAGCUGCCCAAGAAUGGAA… | 3442 nt | 0.3698 |
| SOX2-OT:85 | AAUGCAUUUGCUUUCAGCCGCAGAGAGAAGAAGCUGCCCAAGAAUGGAA… | 3550 nt | 0.3727 |
| SOX2-OT:86 | GCAUUUGCUUUCAGCCGCAGAGAGAAGAAGCUGCCCAAGAAUGGAAAGG… | 1068 nt | 0.3605 |
| SOX2-OT:87 | AGUAGCUUUUAAAGCUGGGCCUUAGUGGGACUCUAAAUGCAAUGAAAGC… | 2234 nt | 0.3926 |
| SOX2-OT:88 | AUGUGCAUUUUGUAGGAAGAAAACUGUGAAUGGAAAAAGGAGAAGGGGA… | 3132 nt | 0.3506 |
| SOX2-OT:89 | GUGAAUGGAAAAAGGAGAAGGGGAGAGAAACGGGGGAAAUCUGGAUAAU… | 1884 nt | 0.3588 |
| SOX2-OT:9 | AAUGCAUUUGCUUUCAGCCGCAGAGAGAAGAAGCUGCCCAAGAAUGGAA… | 3439 nt | 0.3702 |
| SOX2-OT:90 | ACUGACUUCUCCUGCAUUGCUCUCAUAAGGACCCCGGUCAUUACCUCAG… | 4109 nt | 0.3741 |
| SOX2-OT:91 | UGACUUCUCCUGCAUUGCUCUCAUAAGGACCCCGGUCAUUACCUCAGGC… | 1115 nt | 0.3722 |
| SOX2-OT:92 | AAAAAUGUUGAAUAUCAACAAUGGGUUUCAGUGCUGUAUUGUUGAGUUU… | 3141 nt | 0.3483 |
Showing 111 to 120 of 127 entries
Summary
This gene produces alternatively spliced long non-coding RNAs. These RNAs were observed to be upregulated in tumor cells and positively correlated to expression of the SRY-box 2 gene. Overexpression of these transcripts may promote cell proliferation. [provided by RefSeq, Dec 2017]
Forensic Context
A study in human postmortem brain tissue identified the long noncoding RNA SOX2-OT as being upregulated in the dorsolateral prefrontal cortex of subjects with opioid use disorder compared to non-psychiatric controls [Mendez et al. DOI:10.1038/s41380-021-01259-y].