Basic Information
Symbol
SOX2-OT
RNA class
lncRNA
Alias
DKFZp761J1324
ENSG00000242808
ENSG00000242808.1
ENSG00000242808.3
ENSG00000242808.7
ENSG00000242808.8
ENSG00000243341
ENSG00000243341.1
NCRNA00043
OTTHUMG00000158186.2
OTTHUMG00000158221.1
RP11-436A20.3
RP11-4B14.2
Location (GRCh38)
3:180989762-181836880
Forensic tag(s)
Forensic psychiatry evaluation
Drug abuse diagnoses
Transcripts
| ID | Sequence | Length | GC content |
|---|---|---|---|
| SOX2-OT:109 | GGGAUUGCAGUGGCAAAGCUAGGCUAGGUCUUGGAGGCUGGUGUAAGGC… | 745 nt | 0.4658 |
| SOX2-OT:11 | UUUCUCCAUCCUAGUAAUCAAAUUUGAGCAAAAUCAAAUGGGGCUUUCU… | 1342 nt | 0.4240 |
| SOX2-OT:110 | GGGAUUGCAGUGGCAAAGCUAGGCUAGGUCUUGGAGGCUGGUGUAAGGC… | 512 nt | 0.5137 |
| SOX2-OT:111 | GGGAUUGCAGUGGCAAAGCUAGGCUAGGUCUUGGAGGCUGGUGUAAGGC… | 772 nt | 0.4922 |
| SOX2-OT:112 | GGGAUUGCAGUGGCAAAGCUAGGCUAGGUCUUGGAGGCUGGUGUAAGGC… | 383 nt | 0.4778 |
| SOX2-OT:113 | GGGAUUGCAGUGGCAAAGCUAGGCUAGGUCUUGGAGGCUGGUGUAAGGC… | 677 nt | 0.4535 |
| SOX2-OT:114 | GGGAUUGCAGUGGCAAAGCUAGGCUAGGUCUUGGAGGCUGGUGUAAGGC… | 759 nt | 0.4506 |
| SOX2-OT:115 | GGGAUUGCAGUGGCAAAGCUAGGCUAGGUCUUGGAGGCUGGUGUAAGAC… | 836 nt | 0.2955 |
| SOX2-OT:116 | GGGAUUGCAGUGGCAAAGCUAGGCUAGGUCUUGGAGGCUGGUGUAAGGC… | 789 nt | 0.4740 |
| SOX2-OT:117 | GGGAUUGCAGUGGCAAAGCUAGGCUAGGUCUUGGAGGCUGGUGUAAGGC… | 619 nt | 0.4960 |
Showing 11 to 20 of 127 entries
Summary
This gene produces alternatively spliced long non-coding RNAs. These RNAs were observed to be upregulated in tumor cells and positively correlated to expression of the SRY-box 2 gene. Overexpression of these transcripts may promote cell proliferation. [provided by RefSeq, Dec 2017]
Forensic Context
A study in human postmortem brain tissue identified the long noncoding RNA SOX2-OT as being upregulated in the dorsolateral prefrontal cortex of subjects with opioid use disorder compared to non-psychiatric controls [Mendez et al. DOI:10.1038/s41380-021-01259-y].