Basic Information
Symbol
SOX2-OT
RNA class
lncRNA
Alias
DKFZp761J1324
ENSG00000242808
ENSG00000242808.1
ENSG00000242808.3
ENSG00000242808.7
ENSG00000242808.8
ENSG00000243341
ENSG00000243341.1
NCRNA00043
OTTHUMG00000158186.2
OTTHUMG00000158221.1
RP11-436A20.3
RP11-4B14.2
Location (GRCh38)
3:180989762-181836880
Forensic tag(s)
Forensic psychiatry evaluation
Drug abuse diagnoses
Transcripts
| ID | Sequence | Length | GC content |
|---|---|---|---|
| SOX2-OT:118 | GGGAUUGCAGUGGCAAAGCUAGGCUAGGUCUUGGAGGCUGGUGUAAGGC… | 664 nt | 0.4970 |
| SOX2-OT:119 | GGGAUUGCAGUGGCAAAGCUAGGCUAGGUCUUGGAGGCUGGUGUAAGGC… | 798 nt | 0.5013 |
| SOX2-OT:12 | AGUAGCUUUUAAAGCUGGGCCUUAGUGGGACUCUAAAUGCAAUGAAAGC… | 560 nt | 0.4107 |
| SOX2-OT:120 | GGGAUUGCAGUGGCAAAGCUAGGCUAGGUCUUGGAGGCUGGUGUAAGGC… | 850 nt | 0.4635 |
| SOX2-OT:121 | GGGAUUGCAGUGGCAAAGCUAGGCUAGGUCUUGGAGGCUGGUGUAAGGC… | 743 nt | 0.4643 |
| SOX2-OT:122 | AGUGGCAAAGCUAGGCUAGGUCUUGGAGGCUGGUGUAAGGCGAUGUGGG… | 1711 nt | 0.3980 |
| SOX2-OT:123 | UGCCAAUCAAACUGCUACAAGACAACACCCUGAUCUGGCAUGGACAUCG… | 1675 nt | 0.3893 |
| SOX2-OT:124 | AGUCUAGUGGGAGAUGUGGCUGGGGCUAAGAGGAAGAGCUGCAGUUUCC… | 1676 nt | 0.3854 |
| SOX2-OT:125 | GAAAGAGGGAGGGGUGAGGAAAGGGCCAGGACAGUUCCCUCAGUGCCAC… | 1703 nt | 0.4005 |
| SOX2-OT:126 | UGCUUUGAGACUCGGUGGCCUGCAGGCAGCGGGAGACGAGGGGACUGGG… | 1279 nt | 0.3894 |
Showing 21 to 30 of 127 entries
Summary
This gene produces alternatively spliced long non-coding RNAs. These RNAs were observed to be upregulated in tumor cells and positively correlated to expression of the SRY-box 2 gene. Overexpression of these transcripts may promote cell proliferation. [provided by RefSeq, Dec 2017]
Forensic Context
A study in human postmortem brain tissue identified the long noncoding RNA SOX2-OT as being upregulated in the dorsolateral prefrontal cortex of subjects with opioid use disorder compared to non-psychiatric controls [Mendez et al. DOI:10.1038/s41380-021-01259-y].