Basic Information
Symbol
SOX2-OT
RNA class
lncRNA
Alias
DKFZp761J1324
ENSG00000242808
ENSG00000242808.1
ENSG00000242808.3
ENSG00000242808.7
ENSG00000242808.8
ENSG00000243341
ENSG00000243341.1
NCRNA00043
OTTHUMG00000158186.2
OTTHUMG00000158221.1
RP11-436A20.3
RP11-4B14.2
Location (GRCh38)
3:180989762-181836880
Forensic tag(s)
Forensic psychiatry evaluation
Drug abuse diagnoses
Transcripts
| ID | Sequence | Length | GC content |
|---|---|---|---|
| SOX2-OT:127 | GACGCCACUGUGCUGUUGCGUCUUGCGCAGCGCAGACACCUCCACUCUG… | 2920 nt | 0.3497 |
| SOX2-OT:128 | UACUUUCGCGAAGCGCAUUAGGAUGUGGGCUCUGGCUUGAGCUCCAAAA… | 1444 nt | 0.3899 |
| SOX2-OT:13 | AUGUGCAUUUUGUAGGAAGAAAACUGUGAAUGGAAAAAGGAGAAGGGGA… | 561 nt | 0.3779 |
| SOX2-OT:14 | AUGUGCAUUUUGUAGGAAGAAAACUGUGAAUGGAAAAAGGAGAAGGGGA… | 3129 nt | 0.3509 |
| SOX2-OT:15 | GAGGGGAAAGGCAUAGAGAAAAAGGGGAGAAGACACUCUUGCAAAAGAA… | 649 nt | 0.4099 |
| SOX2-OT:16 | GAAUGUUGGGAACCGAUCUGAUUCCAAGGAUUGAGAAGUUUUGCAGUGG… | 864 nt | 0.4537 |
| SOX2-OT:17 | AAUGUUGGGAACCGAUCUGAUUCCAAGGAUUGAGAAGUUUUGCAGUGGU… | 716 nt | 0.4120 |
| SOX2-OT:18 | GAUUCCAAGGAUUGAGAAGUUUUGCAGUGGUCAACUGGUAUAGACAUCC… | 847 nt | 0.4510 |
| SOX2-OT:19 | AAGGAUUGAGAAGUUUUGCAGUGGUCAACUGGUAUAGACAUCCCAUUAC… | 675 nt | 0.4370 |
| SOX2-OT:2 | GUCGUAAAAGGGGACGCGGAGGAGAAGGAAAGUCGCUCAAGCAGUGGAC… | 751 nt | 0.3822 |
Showing 31 to 40 of 127 entries
Summary
This gene produces alternatively spliced long non-coding RNAs. These RNAs were observed to be upregulated in tumor cells and positively correlated to expression of the SRY-box 2 gene. Overexpression of these transcripts may promote cell proliferation. [provided by RefSeq, Dec 2017]
Forensic Context
A study in human postmortem brain tissue identified the long noncoding RNA SOX2-OT as being upregulated in the dorsolateral prefrontal cortex of subjects with opioid use disorder compared to non-psychiatric controls [Mendez et al. DOI:10.1038/s41380-021-01259-y].