Basic Information
Symbol
SOX2-OT
RNA class
lncRNA
Alias
DKFZp761J1324
ENSG00000242808
ENSG00000242808.1
ENSG00000242808.3
ENSG00000242808.7
ENSG00000242808.8
ENSG00000243341
ENSG00000243341.1
NCRNA00043
OTTHUMG00000158186.2
OTTHUMG00000158221.1
RP11-436A20.3
RP11-4B14.2
Location (GRCh38)
3:180989762-181836880
Forensic tag(s)
Forensic psychiatry evaluation
Drug abuse diagnoses
Transcripts
| ID | Sequence | Length | GC content |
|---|---|---|---|
| SOX2-OT:20 | UUGCAGUGGUCAACUGGUAUAGACAUCCCAUUACCACUACUUCCUUCAU… | 348 nt | 0.4023 |
| SOX2-OT:21 | AUAAUCAAACUUUACCUUUACGUAGAACUAAAAGAAGCAUUCCAUGCUA… | 578 nt | 0.3616 |
| SOX2-OT:22 | AUAAUCAAACUUUACCUUUACGUAGAACUAAAAGAAGCAUUCCAUGCUA… | 1252 nt | 0.3850 |
| SOX2-OT:23 | UCCCCUCUAGCCACUACUUCCUUCAUUGGACUGCAAGGUAUUUCUGUUU… | 454 nt | 0.3943 |
| SOX2-OT:24 | CACUACUUCCUUCAUUGGACUGCAAGGUAUUUCUGUUUGGAAAAGUAAU… | 3576 nt | 0.3641 |
| SOX2-OT:25 | CUCUAAUAGUCUAUCUAAUGACUUGAUGUACAGACAGUCUCUGACUUAC… | 737 nt | 0.4464 |
| SOX2-OT:26 | AAAAAUGUUGAAUAUCAACAAUGGGUUUCAGUGCUGUAUUGUUGAGUUU… | 606 nt | 0.3696 |
| SOX2-OT:27 | AAAAAUGUUGAAUAUCAACAAUGGGUUUCAGUGCUGUAUUGUUGAGUUU… | 3532 nt | 0.3669 |
| SOX2-OT:28 | AAAAAUGUUGAAUAUCAACAAUGGGUUUCAGUGCUGUAUUGUUGAGUUU… | 3424 nt | 0.3639 |
| SOX2-OT:29 | AAAAAUGUUGAAUAUCAACAAUGGGUUUCAGUGCUGUAUUGUUGAGUUU… | 3138 nt | 0.3486 |
Showing 41 to 50 of 127 entries
Summary
This gene produces alternatively spliced long non-coding RNAs. These RNAs were observed to be upregulated in tumor cells and positively correlated to expression of the SRY-box 2 gene. Overexpression of these transcripts may promote cell proliferation. [provided by RefSeq, Dec 2017]
Forensic Context
A study in human postmortem brain tissue identified the long noncoding RNA SOX2-OT as being upregulated in the dorsolateral prefrontal cortex of subjects with opioid use disorder compared to non-psychiatric controls [Mendez et al. DOI:10.1038/s41380-021-01259-y].