Basic Information
Symbol
SOX2-OT
RNA class
lncRNA
Alias
DKFZp761J1324
ENSG00000242808
ENSG00000242808.1
ENSG00000242808.3
ENSG00000242808.7
ENSG00000242808.8
ENSG00000243341
ENSG00000243341.1
NCRNA00043
OTTHUMG00000158186.2
OTTHUMG00000158221.1
RP11-436A20.3
RP11-4B14.2
Location (GRCh38)
3:180989762-181836880
Forensic tag(s)
Forensic psychiatry evaluation
Drug abuse diagnoses
Transcripts
| ID | Sequence | Length | GC content |
|---|---|---|---|
| SOX2-OT:3 | GUCGUAAAAGGGGACGCGGAGGAGAAGGAAAGUCGCUCAAGCAGUGGAC… | 836 nt | 0.4629 |
| SOX2-OT:30 | AGUGCUGUAUUGUUGAGUUUUGUAUGAACUAAUCUAGCUUCUCUAAAAA… | 2508 nt | 0.3684 |
| SOX2-OT:31 | AGUGCAUUUGAAAACUCCCCUUGCACCAGGGCUGACUGUAGCUGGGGGA… | 882 nt | 0.4660 |
| SOX2-OT:32 | AUUUGAAAACUCCCCUUGCACCAGGGCUGACUGUAGCUGGGGGAAGACA… | 560 nt | 0.4196 |
| SOX2-OT:33 | CCCUUGCACCAGGGCUGACUGUAGCUGGGGGAAGACAUUUUACUCAUUU… | 561 nt | 0.4813 |
| SOX2-OT:34 | UCAGCUGGUCCCUCUUCUCAGGUGUAGAUCACCUAUUAUAAUUUUACCU… | 979 nt | 0.4505 |
| SOX2-OT:35 | ACCCUCUCUCUCUUCUCUCUCUCCCUCUCCCUCUCUCUCUCUCUCUCUC… | 902 nt | 0.4435 |
| SOX2-OT:36 | CUCUCUCUCUUCUCUCUCUCCCUCUCCCUCUCUCUCUCUCUCUCUCUUU… | 926 nt | 0.4644 |
| SOX2-OT:37 | GCAGGGGAUUGCAGUGGCAAAGCUAGGCUAGGUCUUGGAGGCUGGUGUA… | 387 nt | 0.4806 |
| SOX2-OT:38 | CAGGGGAUUGCAGUGGCAAAGCUAGGCUAGGUCUUGGAGGCUGGUGUAA… | 792 nt | 0.4747 |
Showing 51 to 60 of 127 entries
Summary
This gene produces alternatively spliced long non-coding RNAs. These RNAs were observed to be upregulated in tumor cells and positively correlated to expression of the SRY-box 2 gene. Overexpression of these transcripts may promote cell proliferation. [provided by RefSeq, Dec 2017]
Forensic Context
A study in human postmortem brain tissue identified the long noncoding RNA SOX2-OT as being upregulated in the dorsolateral prefrontal cortex of subjects with opioid use disorder compared to non-psychiatric controls [Mendez et al. DOI:10.1038/s41380-021-01259-y].