Basic Information
Symbol
SOX2-OT
RNA class
lncRNA
Alias
DKFZp761J1324
ENSG00000242808
ENSG00000242808.1
ENSG00000242808.3
ENSG00000242808.7
ENSG00000242808.8
ENSG00000243341
ENSG00000243341.1
NCRNA00043
OTTHUMG00000158186.2
OTTHUMG00000158221.1
RP11-436A20.3
RP11-4B14.2
Location (GRCh38)
3:180989762-181836880
Forensic tag(s)
Forensic psychiatry evaluation
Drug abuse diagnoses
Transcripts
| ID | Sequence | Length | GC content |
|---|---|---|---|
| SOX2-OT:39 | CAGGGGAUUGCAGUGGCAAAGCUAGGCUAGGUCUUGGAGGCUGGUGUAA… | 610 nt | 0.5066 |
| SOX2-OT:4 | GGACGCGGAGGAGAAGGAAAGUCGCUCAAGCAGUGGACAGAGCGGAGAA… | 566 nt | 0.4187 |
| SOX2-OT:40 | CAGGGGAUUGCAGUGGCAAAGCUAGGCUAGGUCUUGGAGGCUGGUGUAA… | 629 nt | 0.4944 |
| SOX2-OT:41 | CAGGGGAUUGCAGUGGCAAAGCUAGGCUAGGUCUUGGAGGCUGGUGUAA… | 472 nt | 0.5148 |
| SOX2-OT:42 | CAGGGGAUUGCAGUGGCAAAGCUAGGCUAGGUCUUGGAGGCUGGUGUAA… | 515 nt | 0.5146 |
| SOX2-OT:43 | CAGGGGAUUGCAGUGGCAAAGCUAGGCUAGGUCUUGGAGGCUGGUGUAA… | 756 nt | 0.4881 |
| SOX2-OT:44 | CAGGGGAUUGCAGUGGCAAAGCUAGGCUAGGUCUUGGAGGCUGGUGUAA… | 667 nt | 0.4978 |
| SOX2-OT:45 | CAGGGGAUUGCAGUGGCAAAGCUAGGCUAGGUCUUGGAGGCUGGUGUAA… | 839 nt | 0.2968 |
| SOX2-OT:46 | CAGGGGAUUGCAGUGGCAAAGCUAGGCUAGGUCUUGGAGGCUGGUGUAA… | 853 nt | 0.4642 |
| SOX2-OT:47 | CAGGGGAUUGCAGUGGCAAAGCUAGGCUAGGUCUUGGAGGCUGGUGUAA… | 748 nt | 0.4666 |
Showing 61 to 70 of 127 entries
Summary
This gene produces alternatively spliced long non-coding RNAs. These RNAs were observed to be upregulated in tumor cells and positively correlated to expression of the SRY-box 2 gene. Overexpression of these transcripts may promote cell proliferation. [provided by RefSeq, Dec 2017]
Forensic Context
A study in human postmortem brain tissue identified the long noncoding RNA SOX2-OT as being upregulated in the dorsolateral prefrontal cortex of subjects with opioid use disorder compared to non-psychiatric controls [Mendez et al. DOI:10.1038/s41380-021-01259-y].