Basic Information
Symbol
SOX2-OT
RNA class
lncRNA
Alias
DKFZp761J1324
ENSG00000242808
ENSG00000242808.1
ENSG00000242808.3
ENSG00000242808.7
ENSG00000242808.8
ENSG00000243341
ENSG00000243341.1
NCRNA00043
OTTHUMG00000158186.2
OTTHUMG00000158221.1
RP11-436A20.3
RP11-4B14.2
Location (GRCh38)
3:180989762-181836880
Forensic tag(s)
Forensic psychiatry evaluation
Drug abuse diagnoses
Transcripts
| ID | Sequence | Length | GC content |
|---|---|---|---|
| SOX2-OT:48 | CAGGGGAUUGCAGUGGCAAAGCUAGGCUAGGUCUUGGAGGCUGGUGUAA… | 775 nt | 0.4929 |
| SOX2-OT:49 | CAGGGGAUUGCAGUGGCAAAGCUAGGCUAGGUCUUGGAGGCUGGUGUAA… | 746 nt | 0.4651 |
| SOX2-OT:5 | ACGCGGAGGAGAAGGAAAGUCGCUCAAGCAGUGGACAGAGCGGAGAAAG… | 1012 nt | 0.4713 |
| SOX2-OT:50 | CAGGGGAUUGCAGUGGCAAAGCUAGGCUAGGUCUUGGAGGCUGGUGUAA… | 693 nt | 0.4690 |
| SOX2-OT:51 | CAGGGGAUUGCAGUGGCAAAGCUAGGCUAGGUCUUGGAGGCUGGUGUAA… | 876 nt | 0.4737 |
| SOX2-OT:52 | CAGGGGAUUGCAGUGGCAAAGCUAGGCUAGGUCUUGGAGGCUGGUGUAA… | 622 nt | 0.4968 |
| SOX2-OT:53 | CAGGGGAUUGCAGUGGCAAAGCUAGGCUAGGUCUUGGAGGCUGGUGUAA… | 762 nt | 0.4514 |
| SOX2-OT:54 | CAGGGGAUUGCAGUGGCAAAGCUAGGCUAGGUCUUGGAGGCUGGUGUAA… | 680 nt | 0.4544 |
| SOX2-OT:55 | CAGGGGAUUGCAGUGGCAAAGCUAGGCUAGGUCUUGGAGGCUGGUGUAA… | 801 nt | 0.5019 |
| SOX2-OT:56 | GGGAUUGCAGUGGCAAAGCUAGGCUAGGUCUUGGAGGCUGGUGUAAGGC… | 581 nt | 0.4974 |
Showing 71 to 80 of 127 entries
Summary
This gene produces alternatively spliced long non-coding RNAs. These RNAs were observed to be upregulated in tumor cells and positively correlated to expression of the SRY-box 2 gene. Overexpression of these transcripts may promote cell proliferation. [provided by RefSeq, Dec 2017]
Forensic Context
A study in human postmortem brain tissue identified the long noncoding RNA SOX2-OT as being upregulated in the dorsolateral prefrontal cortex of subjects with opioid use disorder compared to non-psychiatric controls [Mendez et al. DOI:10.1038/s41380-021-01259-y].