Basic Information
Symbol
SOX2-OT
RNA class
lncRNA
Alias
DKFZp761J1324
ENSG00000242808
ENSG00000242808.1
ENSG00000242808.3
ENSG00000242808.7
ENSG00000242808.8
ENSG00000243341
ENSG00000243341.1
NCRNA00043
OTTHUMG00000158186.2
OTTHUMG00000158221.1
RP11-436A20.3
RP11-4B14.2
Location (GRCh38)
3:180989762-181836880
Forensic tag(s)
Forensic psychiatry evaluation
Drug abuse diagnoses
Transcripts
| ID | Sequence | Length | GC content |
|---|---|---|---|
| SOX2-OT:57 | GGAUUGCAGUGGCAAAGCUAGGCUAGGUCUUGGAGGCUGGUGUAAGGCG… | 762 nt | 0.4593 |
| SOX2-OT:58 | GGAUUGCAGUGGCAAAGCUAGGCUAGGUCUUGGAGGCUGGUGUAAGGCG… | 905 nt | 0.4751 |
| SOX2-OT:59 | GGCUAGGUCUUGGAGGCUGGUGUAAGGCGAUGUGGGUGAAGGCAGGAGG… | 954 nt | 0.3816 |
| SOX2-OT:6 | GGUCUGCUGGAGUUUGCUGGAGGUGCACUCCAGACUCUGUUUGCCUGCC… | 507 nt | 0.3984 |
| SOX2-OT:60 | GGCUAGGUCUUGGAGGCUGGUGUAAGGCGAUGUGGGUGAAGGCAGGAGG… | 495 nt | 0.5515 |
| SOX2-OT:61 | GGCUAGGUCUUGGAGGCUGGUGUAAGGCGAUGUGGGUGAAGGCAGGAGG… | 660 nt | 0.4879 |
| SOX2-OT:62 | GGCUAGGUCUUGGAGGCUGGUGUAAGGCGAUGUGGGUGAAGGCAGGAGG… | 572 nt | 0.5017 |
| SOX2-OT:63 | GGCUAGGUCUUGGAGGCUGGUGUAAGGCGAUGUGGGUGAAGGCAGGAGG… | 575 nt | 0.5148 |
| SOX2-OT:64 | CUAGGUCUUGGAGGCUGGUGUAAGGCGAUGUGGGUGAAGGCAGGAGGCU… | 445 nt | 0.4562 |
| SOX2-OT:65 | UGCCAAUCAAACUGCUACAAGACAACACCCUGAUCUGGCAUGGACAUCG… | 618 nt | 0.4822 |
Showing 81 to 90 of 127 entries
Summary
This gene produces alternatively spliced long non-coding RNAs. These RNAs were observed to be upregulated in tumor cells and positively correlated to expression of the SRY-box 2 gene. Overexpression of these transcripts may promote cell proliferation. [provided by RefSeq, Dec 2017]
Forensic Context
A study in human postmortem brain tissue identified the long noncoding RNA SOX2-OT as being upregulated in the dorsolateral prefrontal cortex of subjects with opioid use disorder compared to non-psychiatric controls [Mendez et al. DOI:10.1038/s41380-021-01259-y].