Basic Information
Symbol
SYNE1-AS1
RNA class
lncRNA
Alias
SYNE1 Antisense RNA 1
SYNE1 Antisense RNA 1 (Non-Protein Coding)
NONHSAG045169.2
HSALNG0054396
Location (GRCh38)
6:152380297-152382335
Forensic tag(s)
Sudden cardiac death diagnosis
External database
Transcripts
| ID | Sequence | Length | GC content |
|---|---|---|---|
| HSALNT0115281 | GGGCAUUAUAAAACUGGAAAUAUUGAAAAGGCUUUCAAAGAUACUGUUU… | 1573 nt | 0.4024 |
| HSALNT0115283 | AGCUAAUCGGGGAGAUAACUAUUUGCUGUGCUGUAGGAGAUUACCAAGA… | 553 nt | 0.5081 |
| HSALNT0337845 | AAAACCACACAGAGGAGAGCUAAUCGGGGAGAUAACUAUUUGCUGUGCU… | 718 nt | 0.4875 |
| HSALNT0337846 | GAGCUAAUCGGGGAGAUAACUAUUUGCUGUGCUGUAGGAGAUUACCAAG… | 553 nt | 0.5099 |
Summary
No relevant information is available at the moment.
Forensic Context
A review of long noncoding RNAs in cardiovascular diseases noted that the SYNE1-AS1 promotes cardiac hypertrophy in humans and other species by acting as a competitive endogenous RNA (ceRNA) that sponges miR-525-5p to derepress SP1, forming a positive feedback loop [Yeh et al. DOI:10.1186/s12929-020-00647-w].