Basic Information

Symbol
ZEB2-AS1
RNA class
lncRNA
Alias
ENSG00000238057.2 ENSG00000238057.4 ENSG00000238057.8 OTTHUMG00000153879.2 ZEB2NAT
Location (GRCh38)
2:144518200-144521477
UCSC Genome Browser Search in Marker Scope
Forensic tag(s)
Other applications
External database
HGNC NCBI Ensembl LNCipedia RNAcentral

Transcripts

ID Sequence Length GC content
ZEB2-AS1:10 UGUAACAGAUGCAAACUGUAACACAAGGGCCAUUAACCCUUUCUCUGCC… 888 nt 0.4651
ZEB2-AS1:11 ACGCCCCACACCUAUUGUCUCCUGUGCUAGAAGCUUUGCAGAAAACCUG… 368 nt 0.5054
ZEB2-AS1:12 AUGAAAUAAAGAAAUGAAACUCGCUAAGCAGACAAAAACAGACAACUUU… 446 nt 0.4798
ZEB2-AS1:13 AAACAGACAACUUUCUGCUUAGAAAACAGCCUUCUCGGUGGGAGAGGAU… 562 nt 0.4769
ZEB2-AS1:14 CUCAAUAAAACUUUUCCUGGGCUGGAUAGCAAAGGACACCUUUGGUUAC… 430 nt 0.4628
ZEB2-AS1:15 CUCAAUAAAACUUUUCCUGGGCUGGAUAGCAAAGGACACCUUUGGUUAC… 429 nt 0.4639
ZEB2-AS1:16 CUCAAUAAAACUUUUCCUGGGCUGGAUAGCAAAGGACACCUUUGGUUAC… 436 nt 0.4587
ZEB2-AS1:17 ACCUUUGGUUACCUGAAUGAACAGUUUUGGCCAGAAAUGGUGAGAAGAA… 531 nt 0.5311
ZEB2-AS1:18 GGAGAGAAAAGCAAGGAGAGAGAGUGUGAGUGUAAGAGAAAGCGAAGAA… 634 nt 0.4921
ZEB2-AS1:19 AAUGAGAAAAUUAGAAAAGGAGGAUGGAGGACGAGCACACCAAAAAGGG… 453 nt 0.4614
Showing 1 to 10 of 31 entries
Summary

This gene produces a spliced long non-coding RNA which is a natural antisense transcript corresponding to the 5' UTR of zinc finger E-box binding homeobox 2 (ZEB2). It is thought that this transcript may be involved in the regulation of ZEB2 expression, and may play a role in the progression of bladder cancer. [provided by RefSeq, Aug 2015]

Forensic Context

A review of long non-coding RNAs in mammals, including humans and mice, synthesized findings that the ZEB2-AS1 complements the 5′ splice site of an intron in the 5′ UTR of Zeb2 mRNA, preventing splicing and allowing translation via an internal ribosome entry site (IRES) in the retained intron [Mercer et al. DOI:10.1038/nrg2521].