Basic Information

Symbol
ZEB2-AS1
RNA class
lncRNA
Alias
ENSG00000238057.2 ENSG00000238057.4 ENSG00000238057.8 OTTHUMG00000153879.2 ZEB2NAT
Location (GRCh38)
2:144518200-144521477
UCSC Genome Browser Search in Marker Scope
Forensic tag(s)
Other applications
External database
HGNC NCBI Ensembl LNCipedia RNAcentral

Transcripts

ID Sequence Length GC content
ZEB2-AS1:20 CCGGGUCCUCAAUCCAGAUAGUCUCUUCUUAUACAGAUAUCUCUAAUGA… 800 nt 0.3850
ZEB2-AS1:22 AAGAAAGGAAAGAGAAAGUCCAACCACUACGGCAAUACUUUUAAGCUCU… 905 nt 0.4696
ZEB2-AS1:23 AAGAAAGGAAAGAGAAAGUCCAACCACUACGGCAAUACUUUUAAGCUCU… 807 nt 0.4746
ZEB2-AS1:24 AAGAAAGGAAAGAGAAAGUCCAACCACUACGGCAAUACUUUUAAGCUCU… 804 nt 0.4701
ZEB2-AS1:25 AAGGGCCAUUAACCCUUUCUCUGCCGGGCACACUCAGUCCCCACGCCCC… 780 nt 0.4462
ZEB2-AS1:26 AAGGGCCAUUAACCCUUUCUCUGCCGGGCACACUCAGUCCCCACGCCCC… 864 nt 0.4676
ZEB2-AS1:27 AAGGGCCAUUAACCCUUUCUCUGCCGGGCACACUCAGUCCCCACGCCCC… 497 nt 0.4909
ZEB2-AS1:28 AGCCUUCUCGGUGGGAGAGGAUGAACUGCCAUGUCUAAGAGAAAGACUU… 384 nt 0.5052
ZEB2-AS1:29 AGCCUUCUCGGUGGGAGAGGAUGAACUGCCAUGUCUAAGAGAAAGACUU… 984 nt 0.4522
ZEB2-AS1:3 CUUAAGAAAGGAAAGAGAAAGUCCAACCACUACGGCAAUACUUUUAAGC… 810 nt 0.4741
Showing 11 to 20 of 31 entries
Summary

This gene produces a spliced long non-coding RNA which is a natural antisense transcript corresponding to the 5' UTR of zinc finger E-box binding homeobox 2 (ZEB2). It is thought that this transcript may be involved in the regulation of ZEB2 expression, and may play a role in the progression of bladder cancer. [provided by RefSeq, Aug 2015]

Forensic Context

A review of long non-coding RNAs in mammals, including humans and mice, synthesized findings that the ZEB2-AS1 complements the 5′ splice site of an intron in the 5′ UTR of Zeb2 mRNA, preventing splicing and allowing translation via an internal ribosome entry site (IRES) in the retained intron [Mercer et al. DOI:10.1038/nrg2521].