Basic Information

Symbol
ZEB2-AS1
RNA class
lncRNA
Alias
ENSG00000238057.2 ENSG00000238057.4 ENSG00000238057.8 OTTHUMG00000153879.2 ZEB2NAT
Location (GRCh38)
2:144518200-144521477
UCSC Genome Browser Search in Marker Scope
Forensic tag(s)
Other applications
External database
HGNC NCBI Ensembl LNCipedia RNAcentral

Transcripts

ID Sequence Length GC content
ZEB2-AS1:30 AGCCUUCUCGGUGGGAGAGGAUGAACUGCCAUGUCUAAGAGAAAGACUU… 896 nt 0.4487
ZEB2-AS1:31 AGCCUUCUCGGUGGGAGAGGAUGAACUGCCAUGUCUAAGAGAAAGACUU… 633 nt 0.4439
ZEB2-AS1:32 GUAGGAGAGAGACGAGAGACCCUGAAACACGCGCCACCUAUCUUUGUGG… 440 nt 0.4273
ZEB2-AS1:33 ACUAAAUCCUACAGAGUACAGGGCGGAAAACGGUGCACACCAUUCACAG… 360 nt 0.4083
ZEB2-AS1:34 ACAGAACUGGAGAACUCCAAGGGGCGAAAGUUAAAGGGAAAGAUCCCGG… 845 nt 0.3893
ZEB2-AS1:4 AAGAAAGGAAAGAGAAAGUCCAACCACUACGGCAAUACUUUUAAGCUCU… 804 nt 0.4701
ZEB2-AS1:5 AAGAAAGGAAAGAGAAAGUCCAACCACUACGGCAAUACUUUUAAGCUCU… 905 nt 0.4696
ZEB2-AS1:6 UGGGAAGAUGCUGUGCCUCGAGGAUUAGUUUAAACAGGGGGCUAUAAAA… 572 nt 0.4825
ZEB2-AS1:7 UGGGAAGAUGCUGUGCCUCGAGGAUUAGUUUAAACAGGGGGCUAUAAAA… 855 nt 0.4444
ZEB2-AS1:8 GCUGUGCCUCGAGGAUUAGUUUAAACAGGGGGCUAUAAAAGAUGUAACA… 1215 nt 0.4675
Showing 21 to 30 of 31 entries
Summary

This gene produces a spliced long non-coding RNA which is a natural antisense transcript corresponding to the 5' UTR of zinc finger E-box binding homeobox 2 (ZEB2). It is thought that this transcript may be involved in the regulation of ZEB2 expression, and may play a role in the progression of bladder cancer. [provided by RefSeq, Aug 2015]

Forensic Context

A review of long non-coding RNAs in mammals, including humans and mice, synthesized findings that the ZEB2-AS1 complements the 5′ splice site of an intron in the 5′ UTR of Zeb2 mRNA, preventing splicing and allowing translation via an internal ribosome entry site (IRES) in the retained intron [Mercer et al. DOI:10.1038/nrg2521].