Basic Information
Symbol
HTT-AS
RNA class
lncRNA
Alias
ENSG00000251075.1
HTT-AS1
HTTAS
OTTHUMG00000159915.4
XLOC_003857
XLOC_003858
linc-NOP14-1
linc-NOP14-2
Location (GRCh38)
4:3048600-3074518
Forensic tag(s)
Forensic psychiatry evaluation
External database
Transcripts
| ID | Sequence | Length | GC content |
|---|---|---|---|
| HTT-AS:1 | AGCAAGGCCGCUGACAGCGCAGCGCCCCACCCGGGCGAAGGCGCGGGGC… | 515 nt | 0.6058 |
| HTT-AS:2 | AGCAAGGCCGCUGACAGCGCAGCGCCCCACCCGGGCGAAGGCGCGGGGC… | 740 nt | 0.5865 |
| HTT-AS:3 | ACACAGCAAGGCCGCUGACAGCGCAGCGCCCCACCCGGGCGAAGGCGCG… | 2528 nt | 0.5028 |
| HTT-AS:4 | ACACAGCAAGGCCGCUGACAGCGCAGCGCCCCACCCGGGCGAAGGCGCG… | 519 nt | 0.6050 |
| HTT-AS:5 | UCAGAAUCAGCGCACAGGAGAAGUGAAGUUUGAGACUUCGAGAAUGAGC… | 326 nt | 0.5245 |
Summary
Predicted to be involved in regulation of gene expression. [provided by Alliance of Genome Resources, Jul 2025]
Forensic Context
The literature review notes that the HTT-AS is detected in the frontal cortex of Huntington's disease patients and functions as a therapeutic target by targeting the HTT gene [Das et al. DOI:10.1080/21655979.2021.2003667].