Basic Information
Symbol
JPX
RNA class
lncRNA
Alias
AL353804.1
DCBALD06
ENOX
ENSG00000225470
ENSG00000225470.1
ENSG00000225470.2
ENSG00000225470.6
ENSG00000225470.7
ENSG00000228906
ENSG00000228906.1
Enox
LINC00183
NCRNA00183
OTTHUMG00000021838.1
OTTHUMG00000021840.1
RP13-216E22.4
Location (GRCh38)
X:73944184-74070832
Forensic tag(s)
Other applications
Transcripts
| ID | Sequence | Length | GC content |
|---|---|---|---|
| JPX:1 | GCUGGGCGCCGGGCCUGUUUGGCUGUGACGCCCACCCCCGGCUUUCAUC… | 2053 nt | 0.4213 |
| JPX:10 | GGAAGACUUAAGAUGGCGGCGUUUGCACGGAGUGCAAUCACUGCGUCCU… | 2194 nt | 0.4216 |
| JPX:11 | GGAAGACUUAAGAUGGCGGCGUUUGCACGGAGUGCAAUCACUGCGUCCU… | 3490 nt | 0.4195 |
| JPX:12 | GAAGACUUAAGAUGGCGGCGUUUGCACGGAGUGCAAUCACUGCGUCCUU… | 829 nt | 0.4717 |
| JPX:13 | AAGACUUAAGAUGGCGGCGUUUGCACGGAGUGCAAUCACUGCGUCCUUA… | 1438 nt | 0.3498 |
| JPX:14 | GACUUAAGAUGGCGGCGUUUGCACGGAGUGCAAUCACUGCGUCCUUACG… | 483 nt | 0.4058 |
| JPX:15 | GACUUAAGAUGGCGGCGUUUGCACGGAGUGCAAUCACUGCGUCCUUACG… | 762 nt | 0.4974 |
| JPX:16 | AAGAUGGCGGCGUUUGCACGGAGUGCAAUCACUGCGUCCUUACGGGGGU… | 476 nt | 0.3887 |
| JPX:17 | CACGGAGUGCAAUCACUGCGUCCUUACGGGGGUUGCAAGGCGUCCGAAG… | 475 nt | 0.4337 |
| JPX:18 | GAAUAAUUUCUUUCUCGCUGAUCGCCUAACUUCUACUGACGAAGCUUGG… | 269 nt | 0.5130 |
Showing 1 to 10 of 49 entries
Summary
JPX is a nonprotein-coding RNA transcribed from a gene within the X-inactivation center (XIC; MIM 314670) that appears to participate in X chromosome inactivation (Tian et al., 2010 [PubMed 21029862]).[supplied by OMIM, Feb 2011]
Forensic Context
A study in humans demonstrated that JPX is overexpressed in females and is known to participate in X-chromosome inactivation [Melé et al. DOI:10.1126/science.aaa0355]. A study in mice demonstrated that the JPX controls binding-site selection by CTCF during early cell differentiation, thereby regulating chromatin topology genome-wide [Mattick et al. DOI:10.1038/s41580-022-00566-8].