Basic Information
Symbol
JPX
RNA class
lncRNA
Alias
AL353804.1
DCBALD06
ENOX
ENSG00000225470
ENSG00000225470.1
ENSG00000225470.2
ENSG00000225470.6
ENSG00000225470.7
ENSG00000228906
ENSG00000228906.1
Enox
LINC00183
NCRNA00183
OTTHUMG00000021838.1
OTTHUMG00000021840.1
RP13-216E22.4
Location (GRCh38)
X:73944184-74070832
Forensic tag(s)
Other applications
Transcripts
| ID | Sequence | Length | GC content |
|---|---|---|---|
| JPX:19 | GUUGGAGUGCAAUGGCGCGAUCUCGGCUGACUGCAACCUCCACCUCCUG… | 2882 nt | 0.3851 |
| JPX:2 | GCUGGGCGCCGGGCCUGUUUGGCUGUGACGCCCACCCCCGGCUUUCAUC… | 1466 nt | 0.3936 |
| JPX:20 | GGGUUUUACCGUGUUAGCCAGGAUGGUCUCGACCUCCUGACCUCGUGAU… | 3833 nt | 0.4044 |
| JPX:21 | UUUUUUUUGUUUUUGAGAUGAAGUCUUGCUCUUGUCACCCAGGCUGGAG… | 451 nt | 0.4390 |
| JPX:22 | UUUCAGUGGUCCUUUUUUAGGUAGUUAUAUUUCUUGUGAAAUAACAUUU… | 8356 nt | 0.3571 |
| JPX:23 | UUAUGCUAUAUGUGAGGAACUGUACUUCACCUGCCUUCCUAUGUACCAG… | 1146 nt | 0.4040 |
| JPX:24 | CCAAAGUGCUGGGAUUACAGGCAUGAGCCACCGCGUCCAGCAAGAAUAG… | 2045 nt | 0.3721 |
| JPX:25 | GCUGAAAUCUUAACACCGAAGAGUUGAAGGCUUUUUCUCUAAGAUCAGG… | 6302 nt | 0.3650 |
| JPX:26 | AUCUCCUGUGAUCCCACGGAGCUGCAGUCAGAAGGGAGCAAUGACAAGA… | 1182 nt | 0.4915 |
| JPX:27 | AUGCCCUAGGGCUAGUGGAAGACUUAAGAUGGCGGCGUUUGCACGGAGU… | 545 nt | 0.5156 |
Showing 11 to 20 of 49 entries
Summary
JPX is a nonprotein-coding RNA transcribed from a gene within the X-inactivation center (XIC; MIM 314670) that appears to participate in X chromosome inactivation (Tian et al., 2010 [PubMed 21029862]).[supplied by OMIM, Feb 2011]
Forensic Context
A study in humans demonstrated that JPX is overexpressed in females and is known to participate in X-chromosome inactivation [Melé et al. DOI:10.1126/science.aaa0355]. A study in mice demonstrated that the JPX controls binding-site selection by CTCF during early cell differentiation, thereby regulating chromatin topology genome-wide [Mattick et al. DOI:10.1038/s41580-022-00566-8].