Basic Information
Symbol
JPX
RNA class
lncRNA
Alias
AL353804.1
DCBALD06
ENOX
ENSG00000225470
ENSG00000225470.1
ENSG00000225470.2
ENSG00000225470.6
ENSG00000225470.7
ENSG00000228906
ENSG00000228906.1
Enox
LINC00183
NCRNA00183
OTTHUMG00000021838.1
OTTHUMG00000021840.1
RP13-216E22.4
Location (GRCh38)
X:73944184-74070832
Forensic tag(s)
Other applications
Transcripts
| ID | Sequence | Length | GC content |
|---|---|---|---|
| JPX:28 | AUGCCCUAGGGCUAGUGGAAGACUUAAGAUGGCGGCGUUUGCACGGAGU… | 25206 nt | 0.3867 |
| JPX:29 | AUGCCCUAGGGCUAGUGGAAGACUUAAGAUGGCGGCGUUUGCACGGAGU… | 579 nt | 0.5060 |
| JPX:3 | CUAUGCCCUAGGGCUAGUGGAAGACUUAAGAUGGCGGCGUUUGCACGGA… | 2212 nt | 0.4227 |
| JPX:30 | AUGCCCUAGGGCUAGUGGAAGACUUAAGAUGGCGGCGUUUGCACGGAGU… | 1488 nt | 0.3864 |
| JPX:31 | AUGCCCUAGGGCUAGUGGAAGACUUAAGAUGGCGGCGUUUGCACGGAGU… | 5132 nt | 0.3504 |
| JPX:32 | AUGCCCUAGGGCUAGUGGAAGACUUAAGAUGGCGGCGUUUGCACGGAGU… | 500 nt | 0.4600 |
| JPX:33 | AUGCCCUAGGGCUAGUGGAAGACUUAAGAUGGCGGCGUUUGCACGGAGU… | 623 nt | 0.4270 |
| JPX:34 | AUGCCCUAGGGCUAGUGGAAGACUUAAGAUGGCGGCGUUUGCACGGAGU… | 7048 nt | 0.3732 |
| JPX:35 | AUGCCCUAGGGCUAGUGGAAGACUUAAGAUGGCGGCGUUUGCACGGAGU… | 1694 nt | 0.4835 |
| JPX:36 | GGAAGACUUAAGAUGGCGGCGUUUGCACGGAGUGCAAUCACUGCGUCCU… | 500 nt | 0.4380 |
Showing 21 to 30 of 49 entries
Summary
JPX is a nonprotein-coding RNA transcribed from a gene within the X-inactivation center (XIC; MIM 314670) that appears to participate in X chromosome inactivation (Tian et al., 2010 [PubMed 21029862]).[supplied by OMIM, Feb 2011]
Forensic Context
A study in humans demonstrated that JPX is overexpressed in females and is known to participate in X-chromosome inactivation [Melé et al. DOI:10.1126/science.aaa0355]. A study in mice demonstrated that the JPX controls binding-site selection by CTCF during early cell differentiation, thereby regulating chromatin topology genome-wide [Mattick et al. DOI:10.1038/s41580-022-00566-8].