Basic Information
Symbol
JPX
RNA class
lncRNA
Alias
AL353804.1
DCBALD06
ENOX
ENSG00000225470
ENSG00000225470.1
ENSG00000225470.2
ENSG00000225470.6
ENSG00000225470.7
ENSG00000228906
ENSG00000228906.1
Enox
LINC00183
NCRNA00183
OTTHUMG00000021838.1
OTTHUMG00000021840.1
RP13-216E22.4
Location (GRCh38)
X:73944184-74070832
Forensic tag(s)
Other applications
Transcripts
| ID | Sequence | Length | GC content |
|---|---|---|---|
| JPX:46 | AUGUUGCCGGCGGAGGCAUUUAGGUAGUGCACGACGGCUGGGCGCCGGG… | 1620 nt | 0.4019 |
| JPX:47 | CUAUGCCCUAGGGCUAGUGGAAGACUUAAGAUGGCGGCGUUUGCACGGA… | 1672 nt | 0.4904 |
| JPX:5 | CUAUGCCCUAGGGCUAGUGGAAGACUUAAGAUGGCGGCGUUUGCACGGA… | 502 nt | 0.4602 |
| JPX:50 | GGUUUCUCCAUGUUGGCCAAGCUGGUCUCAAACUCCUGACCUCAGGUGA… | 1061 nt | 0.3450 |
| JPX:51 | AUUGCUGGCUGCUUCACUCCUGGAACCUUCACUAACCAGAUCCAGGCAG… | 359 nt | 0.5292 |
| JPX:6 | CUAUGCCCUAGGGCUAGUGGAAGACUUAAGAUGGCGGCGUUUGCACGGA… | 625 nt | 0.4272 |
| JPX:7 | CUAUGCCCUAGGGCUAGUGGAAGACUUAAGAUGGCGGCGUUUGCACGGA… | 1670 nt | 0.4910 |
| JPX:8 | UGCCCUAGGGCUAGUGGAAGACUUAAGAUGGCGGCGUUUGCACGGAGUG… | 544 nt | 0.5165 |
| JPX:9 | GCCCUAGGGCUAGUGGAAGACUUAAGAUGGCGGCGUUUGCACGGAGUGC… | 1692 nt | 0.4840 |
Showing 41 to 49 of 49 entries
Summary
JPX is a nonprotein-coding RNA transcribed from a gene within the X-inactivation center (XIC; MIM 314670) that appears to participate in X chromosome inactivation (Tian et al., 2010 [PubMed 21029862]).[supplied by OMIM, Feb 2011]
Forensic Context
A study in humans demonstrated that JPX is overexpressed in females and is known to participate in X-chromosome inactivation [Melé et al. DOI:10.1126/science.aaa0355]. A study in mice demonstrated that the JPX controls binding-site selection by CTCF during early cell differentiation, thereby regulating chromatin topology genome-wide [Mattick et al. DOI:10.1038/s41580-022-00566-8].