Basic Information

Symbol
LEF1-AS1
RNA class
lncRNA
Alias
ENSG00000232021.2 ENSG00000232021.6 OTTHUMG00000161028.1
Location (GRCh38)
4:108171771-108304927
UCSC Genome Browser Search in Marker Scope
Forensic tag(s)
Sudden cardiac death diagnosis
External database
HGNC NCBI Ensembl LNCipedia RNAcentral

Transcripts

ID Sequence Length GC content
LEF1-AS1:10 AGUGCUCCAGGAAAGUACCUGAUUGACAAGAUCUACAUCCAAUGCCCAG… 430 nt 0.4605
LEF1-AS1:11 AGGGGCUGGCUGGAUUGCUGUUGGUUUUUCCCCUCCUGGUGGCUUUGCU… 552 nt 0.4946
LEF1-AS1:12 AGGGGCUGGCUGGAUUGCUGUUGGUUUUUCCCCUCCUGGUGGCUUUGCU… 817 nt 0.5141
LEF1-AS1:13 AGGGGCUGGCUGGAUUGCUGUUGGUUUUUCCCCUCCUGGUGGCUUUGCU… 1413 nt 0.4763
LEF1-AS1:14 AGGGGCUGGCUGGAUUGCUGUUGGUUUUUCCCCUCCUGGUGGCUUUGCU… 1201 nt 0.4671
LEF1-AS1:15 AGGGGCUGGCUGGAUUGCUGUUGGUUUUUCCCCUCCUGGUGGCUUUGCU… 728 nt 0.4492
LEF1-AS1:16 AACACUUCCUUCUACAUCGGGCGCCGUCGCCUCAACUGCGCGUGGGGGG… 1929 nt 0.5765
LEF1-AS1:17 AACACUUCCUUCUACAUCGGGCGCCGUCGCCUCAACUGCGCGUGGGGGG… 1852 nt 0.5761
LEF1-AS1:18 AACACUUCCUUCUACAUCGGGCGCCGUCGCCUCAACUGCGCGUGGGGGG… 1432 nt 0.6306
LEF1-AS1:19 AACACUUCCUUCUACAUCGGGCGCCGUCGCCUCAACUGCGCGUGGGGGG… 1253 nt 0.4190
Showing 1 to 10 of 25 entries
Summary

No relevant information is available at the moment.

Forensic Context

A study in human peripheral blood samples identified LEF1-AS1 as a significantly dysregulated long non-coding RNA associated with both acute myocardial infarction and subsequent myocardial fibrosis, with its expression pattern validated by qRT-PCR and further confirmed in an independent GEO dataset (GSE66360) [Wang et al. DOI:10.2147/IJGM.S329391].