Basic Information
Symbol
LEF1-AS1
RNA class
lncRNA
Alias
ENSG00000232021.2
ENSG00000232021.6
OTTHUMG00000161028.1
Location (GRCh38)
4:108171771-108304927
Forensic tag(s)
Sudden cardiac death diagnosis
External database
Transcripts
| ID | Sequence | Length | GC content |
|---|---|---|---|
| LEF1-AS1:20 | AACACUUCCUUCUACAUCGGGCGCCGUCGCCUCAACUGCGCGUGGGGGG… | 813 nt | 0.4871 |
| LEF1-AS1:21 | AACACUUCCUUCUACAUCGGGCGCCGUCGCCUCAACUGCGCGUGGGGGG… | 2411 nt | 0.5483 |
| LEF1-AS1:22 | CCAGCGCUGGGCCAGUGCAGGCCGAGCCCUGCGUCCCUGCCUCGCUGGG… | 567 nt | 0.6332 |
| LEF1-AS1:23 | CCAGCGCUGGGCCAGUGCAGGCCGAGCCCUGCGUCCCUGCCUCGCUGGG… | 3373 nt | 0.4637 |
| LEF1-AS1:24 | CCAGCGCUGGGCCAGUGCAGGCCGAGCCCUGCGUCCCUGCCUCGCUGGG… | 5409 nt | 0.4600 |
| LEF1-AS1:25 | CCAGCGCUGGGCCAGUGCAGGCCGAGCCCUGCGUCCCUGCCUCGCUGGG… | 462 nt | 0.6688 |
| LEF1-AS1:26 | CCAGCGCUGGGCCAGUGCAGGCCGAGCCCUGCGUCCCUGCCUCGCUGGG… | 470 nt | 0.5872 |
| LEF1-AS1:27 | CCAGCGCUGGGCCAGUGCAGGCCGAGCCCUGCGUCCCUGCCUCGCUGGG… | 683 nt | 0.5681 |
| LEF1-AS1:3 | AAUUGCUAGGGGCUGGCUGGAUUGCUGUUGGUUUUUCCCCUCCUGGUGG… | 559 nt | 0.4919 |
| LEF1-AS1:4 | AAGGACGAGAGAAAAGCACGGUGCCCCUCGAGUCCUCUCCGCCCCCUCG… | 1675 nt | 0.5666 |
Showing 11 to 20 of 25 entries
Summary
No relevant information is available at the moment.
Forensic Context
A study in human peripheral blood samples identified LEF1-AS1 as a significantly dysregulated long non-coding RNA associated with both acute myocardial infarction and subsequent myocardial fibrosis, with its expression pattern validated by qRT-PCR and further confirmed in an independent GEO dataset (GSE66360) [Wang et al. DOI:10.2147/IJGM.S329391].