Forensic Context

A review of studies in human alcoholics and rodent models identified the LINC00092 as a long intergenic non-coding RNA found in co-expression networks from human alcoholic brain RNA-seq data, suggesting a potential role in cellular plasticity shaping alcohol consumption [Mayfield DOI:10.1016/J.Alcohol.2017.01.004]. A study in humans identified the LINC00092 as part of an alcohol-responsive gene module in the prefrontal cortex of individuals with alcohol dependence [Warden & Mayfield 10.1016/J.Neuropharm.2017.02.017], and it was further characterized as a component of co-expression modules associated with lifetime alcohol consumption in postmortem human brain tissue [Farris et al. 10.1038/Mp.2014.159].