Basic Information
Symbol
FXYD2
RNA Class
mRNA
Alias
FXYD domain containing ion transport regulator 2
MGC12372
hypomagnesemia 2, renal
ATP1G1
HOMG2
sodium/potassium-transporting ATPase subunit gamma
ATPase, Na+/K+ transporting, gamma 1 polypeptide
Na(+)/K(+) ATPase subunit gamma
sodium pump gamma chain
ATP1C
Sodium/potassium-transporting ATPase subunit gamma
FXYD domain-containing ion transport regulator 2
Sodium pump gamma chain
Location (GRCh38)
11:117800839-117828698
UCSC Genome Browser
Transcripts
Secondary Structure
MANE Select
NM_001680.5
Sequence length
589 nt
GC Content
0.5857
Secondary Structure
Generated by RNAfold
Minimum free energy (MFE) structure:
Secondary structure that contributes a minimum of free energy.
Secondary structure that contributes a minimum of free energy.
Ensemble properties:
Thermodynamic properties of the Boltzmann ensemble.
Thermodynamic properties of the Boltzmann ensemble.
Minimum free energy
-218.4 kcal/mol
Thermodynamic ensemble
Free Energy:
-227.78 kcal/mol
Frequency:
0.0000
Diversity:
188.66
MFE Structure Visualization
Structure Prediction
MFE Structure Prediction
...........((((((((((((((((.(((.((((.((((((.(....)))))))((((((........)))))).(((....)))(((((.(((((.....(((((((((((((.....))))).......(((((....(((((.(((((((((.(.(((.....)))).))))))))).)))))....)))))(((((.((((.((....)).)))).)))))........((.(((((((.(((......)))(((.......((((((....((((((.....))))))...((((((((((((....)).))).)))))))..((((((((((............((((((((....(((((((((.(((........)))...)))).))))))))).))))((.....)).......(((((((((.((........))...)))))))))...((((......)))).))))))))))...))))))...)))...)))))))))))))))))...))))).)))))..)))))))..)))...(((....)))......)))))...))))))))...
Thermodynamic Ensemble Prediction
...........{(((((((((((({((,((..,(((,((({(({(((((((({,{{((({{{,,...,,,,)))))}||||,,||.,(((((,((({{|||,.((((((({({(((..,..})}}}.......{{(((.,,.,{(((.(((((((((.(.(((.....)))).))))))))).)))))}.},)})}){((((.((((.((....)).)))).))))),.....,.{(,{(((((,.,,{.....,|}|{{{|,{....,||,{{...||{(((({,...}}}}}|...((((((((((((....)),})).)))))))}.((((((((((............{{({(({{....({{{{|||{,|((,.,.....}}}...}))|,}}}}}}))).)))).,,,...}}},.....(((((((((.((........))...)))))))))...((((......)))).))))))))))...))))))}}}))).,})})))))}))))))}}}...||||}.}}||},{|},,,||..|)}...||,....,))}),.,}),,,,...))))))))...
Transcripts
| ID | Sequence | Length | GC Content |
|---|---|---|---|
| NM_001127489.1 | AGACACUCUCCAAAAAGCAGAGACAGCAGGAAGAGGGGAGUGGAGGCAG… | 2747 nt | 0.5701 |
| NM_001680.5 | AGACACUCUCCAAAAAGCAGAGACAGCAGGAAGAGGGGAGUGGAGGCAG… | 589 nt | 0.5857 |
| NM_021603.4 | ACUCUCCAUCCAGGCCCCAGGCAAGCAGCACCUCCCUGCUCUCCUGCAC… | 593 nt | 0.5970 |
Summary
This gene encodes a member of the FXYD family of transmembrane proteins. This particular protein encodes the sodium/potassium-transporting ATPase subunit gamma. Mutations in this gene have been associated with Renal Hypomagnesemia-2. Alternatively spliced transcript variants have been described. Read-through transcripts have been observed between this locus and the upstream FXYD domain-containing ion transport regulator 6 (FXYD6, GeneID 53826) locus.[provided by RefSeq, Feb 2011]
Forensic Context
No forensic context available.
Genomic Tracks
