Basic Information
Symbol
HBD
RNA Class
mRNA
Alias
hemoglobin subunit delta
HBK
hemoglobin, delta
delta globin
delta-globin chain
hemoglobin delta chain
Hemoglobin subunit delta
Delta-globin
Hemoglobin delta chain
Location (GRCh38)
11:5232678-5243657
UCSC Genome Browser
Transcripts
Secondary Structure
MANE Select
NM_000519.4
Sequence length
620 nt
GC Content
0.5065
Secondary Structure
Generated by RNAfold
Minimum free energy (MFE) structure:
Secondary structure that contributes a minimum of free energy.
Secondary structure that contributes a minimum of free energy.
Ensemble properties:
Thermodynamic properties of the Boltzmann ensemble.
Thermodynamic properties of the Boltzmann ensemble.
Minimum free energy
-205.6 kcal/mol
Thermodynamic ensemble
Free Energy:
-217.96 kcal/mol
Frequency:
0.0000
Diversity:
161.04
MFE Structure Visualization
Structure Prediction
MFE Structure Prediction
.((((.((((((((....(((.....((((((((...............(((((((((.((.(((((((((((((((...........((((((.(((((.....((..((((...(((((....((.((((((..(((.((((((....)))))).)))..)).(((((((((((...))).)))))))).......)))).))....)))))))))..))..((..((((((((((.(((.((..((((((((...)))))))).)).)))))))...))))))))....))))))))))))))))))))))..)))).)).)))))))))......(((....(((.(((((.....))))).)))...)))...))))))))..)))((.((((.(((....(((...((......)))))....))).))))))...)))))))).))))(((.(((.(((((......)))))))).)))....(((((...((((((.((((.((..........)).)))).....(((((.((.(((........))))).)))))....((((((.......))))))(((....)))...........)))))))))))
Thermodynamic Ensemble Prediction
.((((.((((((((,,,..,,||||.{{{{{{{,........,,.,,,,(((((((((.((.((((((((((((((((({((,|{{{.(((((....))))}...}},.||,,...}))}}.{{.(({,((((({{((,.,,,,,.}}}}.)))))}))),.|{{(({,{{|||||...,,|,||||||||{...{{{||||....,,{{{{.,...,}})}.,,,..((((((((((.(((.((..((((((((...)))))))).)).)))))))...))))))))})}.)))))))))),)))))))))))..)))).)).)))))))))......{((,{,,(((.((((({...,))))).))),},)}}.}})))))))),.}}}{{.((((.(((..{{(({...((......))}},}}},))).)))))}...)))))))).)))){((,(((,(((((......)))),))).}}},}},{((((...((((((.{(((.,{..........||,||,|.....{((((.((.(((........))))).)))))....((((((.......))))))(((....))).......,,,.)))))))))),
Transcripts
| ID | Sequence | Length | GC Content |
|---|---|---|---|
| NM_000519.4 | ACACUUUCUUCUGACAUAACAGUGUUCACUAGCAACCUCAAACAGACAC… | 620 nt | 0.5065 |
Summary
The delta (HBD) and beta (HBB) genes are normally expressed in the adult: two alpha chains plus two beta chains constitute HbA, which in normal adult life comprises about 97% of the total hemoglobin. Two alpha chains plus two delta chains constitute HbA-2, which with HbF comprises the remaining 3% of adult hemoglobin. Five beta-like globin genes are found within a 45 kb cluster on chromosome 11 in the following order: 5'-epsilon--Ggamma--Agamma--delta--beta-3'. Mutations in the delta-globin gene are associated with beta-thalassemia. [provided by RefSeq, Jul 2008]
Forensic Context
No forensic context available.
Genomic Tracks
