Basic Information
Symbol
IL17F
RNA Class
mRNA
Alias
interleukin 17F
IL-17F
ML-1
ML1
CANDF6
IL17A
interleukin-17F
cytokine ML-1
Interleukin-17F
Cytokine ML-1
Location (GRCh38)
6:52236681-52245689
UCSC Genome Browser
Transcripts
Secondary Structure
MANE Select
NM_052872.4
Sequence length
813 nt
GC Content
0.4748
Secondary Structure
Generated by RNAfold
Minimum free energy (MFE) structure:
Secondary structure that contributes a minimum of free energy.
Secondary structure that contributes a minimum of free energy.
Ensemble properties:
Thermodynamic properties of the Boltzmann ensemble.
Thermodynamic properties of the Boltzmann ensemble.
Minimum free energy
-233.1 kcal/mol
Thermodynamic ensemble
Free Energy:
-250.85 kcal/mol
Frequency:
0.0000
Diversity:
219.73
MFE Structure Visualization
Structure Prediction
MFE Structure Prediction
....(((.((((((((((((((.....(((...)))....)))))))......(((((((.((((.......(((((((.(((((....((((((...)))))).....)).)))...)))))))...)))))))))))(((((((.((.((((((((((((((((((......(((((.....)))))))))))..........)))))).))))))..)))))))))..(.((((.(((.......))).)))))..........((((..((((.((((......)))).))))..))))....(((...(((((......(((((((((((((((......))).))).....))).)).))))(((((((......)).))))).(((....)))....((((.((((..(((....)))..)))).))))..)))))...))).((((((....)))).)).(((......)))..(((((((((.(((.(.(((((((((....((((((.((.((.....)).))))))))))).)).)))).)..((((((((((.(((((((.((....(((((.....)))))..)).))).)))).))))).(((....))).....((((((((........................))))))))............)))))))).)))))))))............))))))).)))..(((((.....(((((((.(.(((..((.(((((((........))))))).))..)))).)))))))...)))))..............
Thermodynamic Ensemble Prediction
....{((.((((((((((((((.,.,.(({...}}}.,,,)))))))......(((((((.((((..,.,,,,({(((({({(((....((((((...)))))).....)).}))}}})))))}}...}))))))))))(((((((.((,((((((((((((((({{,.....,(((((.....))))))}}}}}..........))))))))})))).,)))))))))..|}|{||,|||,..,,,,|}}.}}}}},,}}......((((..((((.((((......)))).))))..)))).{,,((({,.(((((,.,{{{{{,((,,,,((((((......))).)))....}}})||),},,{(((((((......))}}))))}{{,....}}},...((((.((((..(((....)))..)))).))))..,,,}||,,|||.(({((({,.{||}}.))},|,}}},.}),}.)}|||||,,,}|||}}..))|},,|)}}..((((((.((.((.....)).)))))))).{{{{..{(({,{.,((((((((((.(((((((.((....(((((.....)))))..)).)))},))).))))).,,{,{,.}}),....((((((((..{,..................,,)))))))),,,....}}..,))))))).)))).)))).............))))))),))).,||.,,...,{{{((((({{,{,{,,,,.{{{{{{|........}}}},}},}}.,}}}}|}}}}}.....,))))}},...........
Transcripts
| ID | Sequence | Length | GC Content |
|---|---|---|---|
| NM_052872.4 | GAACACAGGCAUACACAGGAAGAUACAUUCACAGAAAGAGCUUCCUGCA… | 813 nt | 0.4748 |
| NM_172343.1 | GGCUUCAGUUACUAGCUAGGCUACUGAGUUUAGUUCUCAGUUUGGCACC… | 919 nt | 0.4755 |
Summary
The protein encoded by this gene is a cytokine that shares sequence similarity with IL17. This cytokine is expressed by activated T cells, and has been shown to stimulate the production of several other cytokines, including IL6, IL8, and CSF2/GM_CSF. This cytokine is also found to inhibit the angiogenesis of endothelial cells and induce endothelial cells to produce IL2, TGFB1/TGFB, and monocyte chemoattractant protein-1. [provided by RefSeq, Jul 2008]
Forensic Context
No forensic context available.
Genomic Tracks
