Basic Information
Symbol
MACF1
RNA Class
mRNA
Alias
microtubule actin crosslinking factor 1
KIAA0465
ACF7
ABP620
KIAA1251
MACF
FLJ45612
FLJ46776
Lnc-PMIF
actin cross-linking factor
620 kDa actin binding protein
macrophin 1
trabeculin-alpha
actin cross-linking family protein 7
postulated migration inhibitory factor
KIAA0754
LIS9
OFC4
microtubule-actin cross-linking factor 1
Microtubule-actin cross-linking factor 1, isoforms 6/7
Uncharacterized protein KIAA0754
Microtubule-actin cross-linking factor 1, isoforms 1/2/3/4/5
620 kDa actin-binding protein
Actin cross-linking family protein 7
Macrophin-1
Trabeculin-alpha
Location (GRCh38)
1:39081316-39487177
UCSC Genome Browser
Transcripts
Secondary Structure
MANE Select
NM_001394062.1
Sequence length
24340 nt
GC Content
0.4598
Transcripts
| ID | Sequence | Length | GC Content |
|---|---|---|---|
| NM_001394062.1 | AGAGGUUUGAGUCAGCUUGACACUGGCUUAGGCGCUCCUUUUCACUCUC… | 24340 nt | 0.4598 |
| NM_001397473.1 | GAGCACUUCCAGCGAGCUAGCGAGCUAGCGGGUCGCGCUGCGCGGGGGA… | 13085 nt | 0.4903 |
| NM_012090.5 | AUCACUUCUCCCUGGGCUCCCAGGCCCUCCUGCAGCAGCCCCCGCCUGG… | 17701 nt | 0.4726 |
| NM_033044.3 | GGCUCUGAUUCAGUUUUCUUUUUCUUCUCUUUUCCUUUUUUUUUUUUUU… | 19349 nt | 0.4534 |
Summary
This gene encodes a large protein containing numerous spectrin and leucine-rich repeat (LRR) domains. The encoded protein is a member of a family of proteins that form bridges between different cytoskeletal elements. This protein facilitates actin-microtubule interactions at the cell periphery and couples the microtubule network to cellular junctions. Alternative splicing results in multiple transcript variants, but the full-length nature of some of these variants has not been determined. [provided by RefSeq, May 2013]
Forensic Context
No forensic context available.
Genomic Tracks
