Basic Information
Symbol
MT-ND6
RNA Class
mRNA
Alias
mitochondrially encoded NADH:ubiquinone oxidoreductase core subunit 6
NAD6
ND6
complex I ND6 subunit
NADH-ubiquinone oxidoreductase chain 6
NADH dehydrogenase 6
mitochondrially encoded NADH dehydrogenase 6
NADH dehydrogenase subunit 6
MTND6
NADH6
EC 7.1.1.2
EC 1.6.5.3
Location (GRCh38)
MT:14149-14673
UCSC Genome Browser
Transcripts
Secondary Structure
MANE Select
NC_012920.1
Sequence length
532 nt
GC Content
0.4211
Secondary Structure
Generated by RNAfold
Minimum free energy (MFE) structure:
Secondary structure that contributes a minimum of free energy.
Secondary structure that contributes a minimum of free energy.
Ensemble properties:
Thermodynamic properties of the Boltzmann ensemble.
Thermodynamic properties of the Boltzmann ensemble.
Minimum free energy
-117 kcal/mol
Thermodynamic ensemble
Free Energy:
-129.26 kcal/mol
Frequency:
0.0000
Diversity:
136.76
MFE Structure Visualization
Structure Prediction
MFE Structure Prediction
(((((.(((((...((((((((.............(.(((((((((((.(.(((((..((.((.(.(((((((((..(((((((.(((((((...((((((((((.(((((((((((.(((....)))))))).............)))))).)..))))))))).........((((((((((.(((....))).))))))))))(((((((((.((.(((((((..((.(...(((((((((....(((((((.......)))))))..)))))))))...).))..))))...........(.(((((.(.......).))))).)...))).)).))))))))).(((.....))).......)))))))..)))))))))))))))).).))))..))))).)..))))))))))).)))))))))...))))))))))((((((((((((.(((((..(((......((((.....))))...)))..))))))))))))...)))))...........
Thermodynamic Ensemble Prediction
..,,,..,,,,.,,((((((.({{{{{.....,.{(.(((((((((((.(.(((((..({{((.(.(((((((((..(((((((.(((((((.,,{(((((((({,((,,,,(((({,{,,....}}}})))}...,{{{{{{{|||||}},.,...))))},))}}}},,,..((((((((((.(((....))).))))))))))(((((((((.((.(((,{{,..{{.,.{{(((((((((....,((((((.,.....))))))}..))))))))}.}},.}|,.|}||.....,....,|.(((((.(.......).))))).}...))).)).))))))))).|||,}}}}))).,,,...)))))))..)))))))))))))))).).))))..))))).).,))))))))))).))|||,,||..,||||||||||{{{{{{((((((((({...,)))))))}}|{{{.,|,,}}}},}}}))}}}},,}},,}}},...})))))}.})))}},.
Summary
Enables NADH dehydrogenase (ubiquinone) activity. Involved in mitochondrial electron transport, NADH to ubiquinone and mitochondrial respiratory chain complex I assembly. Located in mitochondrion. Part of mitochondrial inner membrane. Implicated in Leber hereditary optic neuropathy; Leigh disease; and spinal muscular atrophy with lower extremity predominant 2B. [provided by Alliance of Genome Resources, Nov 2024]
Forensic Context
No forensic context available.
Genomic Tracks
