Basic Information
Symbol
MTO1
RNA Class
mRNA
Alias
mitochondrial tRNA translation optimization 1
mitochondrial translation optimization 1 homolog (S. cerevisiae)
CGI-02
COXPD10
protein MTO1 homolog, mitochondrial
homolog of yeast Mto1
mitochondrial MTO1-3
mitochondrial translation optimization 1 homolog
Protein MTO1 homolog, mitochondrial
EC 1.1.1.40
EC 6.3.5
Location (GRCh38)
6:73461578-73509236
UCSC Genome Browser
Transcripts
Secondary Structure
MANE Select
NM_012123.4
Sequence length
10698 nt
GC Content
0.4245
Transcripts
| ID | Sequence | Length | GC Content |
|---|---|---|---|
| NM_001123226.2 | GUCCUACCCCGUGAUAUUAAAGCAAGAUGGCCGCGCCCUGCAGAUUGUC… | 10818 nt | 0.4261 |
| NM_012123.4 | GUCCUACCCCGUGAUAUUAAAGCAAGAUGGCCGCGCCCUGCAGAUUGUC… | 10698 nt | 0.4245 |
| NM_133645.3 | GUCCUACCCCGUGAUAUUAAAGCAAGAUGGCCGCGCCCUGCAGAUUGUC… | 10773 nt | 0.4256 |
Summary
This gene encodes a mitochondrial protein thought to be involved in mitochondrial tRNA modification. The encoded protein may also play a role in the expression of the non-syndromic and aminoglycoside-induced deafness phenotypes associated with a specific mutation in the mitochondrial 12S rRNA gene. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008]
Forensic Context
No forensic context available.
Genomic Tracks
