Basic Information
Symbol
PF4
RNA Class
mRNA
Alias
platelet factor 4
SCYB4
CXCL4
chemokine (C-X-C motif) ligand 4
PF-4
C-X-C motif chemokine 4
iroplact
oncostatin-A
Platelet factor 4
Iroplact
Oncostatin-A
Location (GRCh38)
4:73980811-73982027
UCSC Genome Browser
Transcripts
Secondary Structure
MANE Select
NM_002619.4
Sequence length
773 nt
GC Content
0.4398
Secondary Structure
Generated by RNAfold
Minimum free energy (MFE) structure:
Secondary structure that contributes a minimum of free energy.
Secondary structure that contributes a minimum of free energy.
Ensemble properties:
Thermodynamic properties of the Boltzmann ensemble.
Thermodynamic properties of the Boltzmann ensemble.
Minimum free energy
-211.2 kcal/mol
Thermodynamic ensemble
Free Energy:
-227.74 kcal/mol
Frequency:
0.0000
Diversity:
184.21
MFE Structure Visualization
Structure Prediction
MFE Structure Prediction
...((((.(((((...(((..(((........)))..)))((((.........))))(((.(((((((....))).)))))))((((..(((.((((.((((..((((((((((((.((.....(((((....))))).......(((((((.(((((..((((......))))..)))...)).)))).)))(((((((.(.(....((((........))))...)))))))))..)).)))))))).))))....)))))))).))).))))....((..(((.((..((((...)))).))..)))..)).......(((((......)))))...(((.(.(((((...............))))).).)))(((((...))))).......((((((............))))))...((((((((((((.......))))).))))))).)))))..(((((((((((.....((((((..............))))))..(((((.(((.((.((........)).)).))).)))))(((((((..((...))..)))))))...((((........))))(((((((...(((((..(((...(((.((.(((.(((((((.((((((((..((.(((..(((((..(((((.......))).))....)))))...))).))...))))))))..))))))))))..)).)))....))).)))))....))))))).))))))))))))))).........
Thermodynamic Ensemble Prediction
...(((({((({{..{(((,.,((,,,{{...,}|,.,,},||,..}.,,,.,})))||.{(((((((....))).)))))}}((((..(((,((((.((((..((((((((((((.(({.(((((((,.,..||,,,.}},{{.{((((((.(({((..((((......))))..)}}},.)).)))).)))|||((((.(.({{..,,,|}}....}}))},..,)))))).))}.,,.)))))))).))))....)))))))))))..))))....{{..(((.{(..((((...)))).}}..)))..)}.....,.{((((.....,|}}}}...}||}|.||||..............,,}},||{.,{(|{(({,.}}})))}}},....((((((............))))))...((((((((((((.......))))).))))))}.,,|||{{(((((({{{{{...,.((((((..............}}}}}}.,,,,,.......((((((((((({{{{,....(((((..(((((((..((...))..)))))))..,((((........))))})))))}}}}}....))))))))))).{(((((((..((((.((((({.....((((....((({,(((((,{{,.{{,{(((({,....,}))}.}).}))).....)))))))))...)))).}))))).))))..))))))}.},.,}}}}})))}),}}}}}}},))))).........
Transcripts
| ID | Sequence | Length | GC Content |
|---|---|---|---|
| NM_001363352.1 | AUCUUAGUUUCCGCACCGCAGUUCCUCGGUGUCCACUUCAGGCUUCCGG… | 1061 nt | 0.4892 |
| NM_002619.4 | AUUGGCCACAGAGACCCAGCCCGAGUUUCCCAUCGCACUGAGCACUGAG… | 773 nt | 0.4398 |
Summary
This gene encodes a member of the CXC chemokine family. This chemokine is released from the alpha granules of activated platelets in the form of a homotetramer which has high affinity for heparin and is involved in platelet aggregation. This protein is chemotactic for numerous other cell type and also functions as an inhibitor of hematopoiesis, angiogenesis and T-cell function. The protein also exhibits antimicrobial activity against Plasmodium falciparum. [provided by RefSeq, Oct 2014]
Forensic Context
No forensic context available.
Genomic Tracks
