Basic Information
Symbol
PPIH
RNA Class
mRNA
Alias
peptidylprolyl isomerase H
USA-CYP
CYP-20
SnuCyp-20
CYPH
MGC5016
USA-CyP SnuCyp-20
cyclophilin H
U-snRNP-associated cyclophilin SunCyp-20
small nuclear ribonucleoprotein particle-specific cyclophilin H
rotamase H
peptidyl-prolyl cis-trans isomerase H
PPIase h
peptidyl prolyl isomerase H (cyclophilin H)
U-snRNP-associated cyclophilin SnuCyp-20
CYP20
Peptidyl-prolyl cis-trans isomerase H
PPIase H
Rotamase H
Small nuclear ribonucleoprotein particle-specific cyclophilin H
CypH
EC 5.2.1.8
Location (GRCh38)
1:42658185-42676758
UCSC Genome Browser
Transcripts
Secondary Structure
MANE Select
NM_006347.4
Sequence length
754 nt
GC Content
0.4735
Secondary Structure
Generated by RNAfold
Minimum free energy (MFE) structure:
Secondary structure that contributes a minimum of free energy.
Secondary structure that contributes a minimum of free energy.
Ensemble properties:
Thermodynamic properties of the Boltzmann ensemble.
Thermodynamic properties of the Boltzmann ensemble.
Minimum free energy
-225 kcal/mol
Thermodynamic ensemble
Free Energy:
-242.16 kcal/mol
Frequency:
0.0000
Diversity:
163.92
MFE Structure Visualization
Structure Prediction
MFE Structure Prediction
(((....(((((((((((((((((((((.(((((((...........)))).)))))))))).)))((((((.(..((....((((((((....))))))))))..).))))))((((.((((((.....((((((((.(......)...))))))))..))))))..))))...((..((.(((((((((..((.((((...((..(((((((..((((((.(((((((.((....)).)))))))...))))))(((((.......)))))((((((((.....))))))))...(((((((((..(.(((((....(((((..((((((((((.((.(...(((((((..(((....((..(((((.((..........)).)))))..))((((..(((((((((((((((((.((..(((........)))..)).)))))))))....((((((.(((....))).))))))........((((....(((((((((...........(((....))).))))))).)))))))))).)))).))))...((((........))))))).)))))))............).)))))))..)))))))))).))))).).)))))))))....))))))).)))))).))..)))))))))..))..)))))).))))))))))((((((....((((...))))))))))...........((((.(((((.....))))).))))..
Thermodynamic Ensemble Prediction
(((....((((((((((((({(((((((.(((((((...........)))},}))))))))).})){(((((.(,.,{....((((((((....))))))))}),.}.))))),((((.((((((.....((((((((..,........,))))))))..))))))..))))...{(..((.(((((((((..((.((((...,,..(((((((..{(((((.(((((((.{,....}}.)))))))...)))))){{{{{.......}))}}{(((((((.....)))))))}...(((((((((..{.(((((....,((((..{(((((((((.((.{,{{(((((((((((((({{((,,(({((,({,,,.......,),))))}|.}}||,,.,{({({((({{{,{|,|{,,,..|||..,}}}}})))}.}}})}}})))))....((((((.(((....))).)))))).......,({((....(((((((((...........{((....))).))))))).))})))})}},}}|||||||{.{((((........))))).},)}}}})),,}|........),))))))},,}))))))))}.))))).}.)))))))))....))))))).}})))).))..)))))))))..))..)})))).)))))))))){(((({....,,,,...}},,})))}}.,,,,....,,|(((.((((({...,))))).))),..
Transcripts
| ID | Sequence | Length | GC Content |
|---|---|---|---|
| NM_001330510.2 | GACUUCUGCUUCCGGGUCGGAGCCAUGGCGGUGGCAAAUUCAAGUCCUG… | 873 nt | 0.4800 |
| NM_006347.4 | GACUUCUGCUUCCGGGUCGGAGCCAUGGCGGUGGCAAAUUCAAGUCCUG… | 754 nt | 0.4735 |
Summary
The protein encoded by this gene is a member of the peptidyl-prolyl cis-trans isomerase (PPIase) family. PPIases catalyze the cis-trans isomerization of proline imidic peptide bonds in oligopeptides and accelerate the folding of proteins. This protein is a specific component of the complex that includes pre-mRNA processing factors PRPF3, PRPF4, and PRPF18, as well as U4/U5/U6 tri-snRNP. This protein has been shown to possess PPIase activity and may act as a protein chaperone that mediates the interactions between different proteins inside the spliceosome. [provided by RefSeq, Jul 2008]
Forensic Context
No forensic context available.
Genomic Tracks
