Basic Information
Symbol
PRB3
RNA Class
mRNA
Alias
proline rich protein BstNI subfamily 3
PRG
G1
basic salivary proline-rich protein 3
BstNI type basic salivary proline-rich protein 3
G1 parotid salivary glycoprotein
parotid salivary glycoprotein G1
proline-rich protein G1
Basic salivary proline-rich protein 3
Parotid salivary glycoprotein G1
Proline-rich protein G1
Secondary Structure
MANE Select
NM_001394862.1
Sequence length
1227 nt
GC Content
0.5860
Secondary Structure
Generated by RNAfold
Minimum free energy (MFE) structure:
Secondary structure that contributes a minimum of free energy.
Secondary structure that contributes a minimum of free energy.
Ensemble properties:
Thermodynamic properties of the Boltzmann ensemble.
Thermodynamic properties of the Boltzmann ensemble.
Minimum free energy
-334.6 kcal/mol
Thermodynamic ensemble
Free Energy:
-358.58 kcal/mol
Frequency:
0.0000
Diversity:
416.38
MFE Structure Visualization
Structure Prediction
MFE Structure Prediction
....((((((((..((((((..(((((.(...((((...))))...).)))))..)))(((((.(((.((((((((((((((......)))))).......(((((.....(((.((...)).))).....))))).((....))....((((((........((((((......((......))......))))))...((...(((....((((...((((....)).))......))))...)))...))...)))))))))...))))).))).))))).......(((((......(((((.(((((..((.(((.((..(((....((....))....)))..)).))).)).............((((..((.(((.((..(((....((....))....)))..)).))).))......((((...(((..((((.......))))...)))....))))..(((((...((((((......((((...(((..((((.......))))...)))....))))...........(((((......(((((..(((((...((((..((((((....((....))....)))......((((((............(((((.........(((.(((.........(((((....((....)).(((......)))...))))).........))).))).........)))))...........((((.......))))..(((((.........(((.(((.........(((((...((.((.(((.((..(((........)))..))..))).))...)).......(((((....))))).....((((.......))))..))))).........))).))).........)))))............((((.....))))...........)))))).))))))).....)))))....(((.(.(((((.........((((...))))..))))).).))).........)))))..))))).))))))...)))))..)))).....))))).....)))))..)))))((.........))(((((((.((((...((((((.(((...........)))...)).))))....)).)).))))))).((((((((........)))))))).....................)))..))).))))).
Thermodynamic Ensemble Prediction
....((((((((.{(({({(..(((((.{...((({...,))}...).})))),,)}}(((((.(((.(((((,(((((({{.,,,,,)}}}}},......{{{{{.,,,..(({.,....},),|||...}}}}}.{{....}}....((((((.{,,,...{(((((......{{......}}......))))))...||...,||....(((({.,{,({....)).||...,,.}}}}...|||...,..},)))))).||...})),}.,||,||,}|,,,....||,((....,.{{{{,..|||,.,|,.|||.||..|||....{{....)),|..|||{,,,.,)).||......,|||...|||||,,,.,,|.||,,|||...,||....||||,.|||{,....}}.||......||||...|||||{{{|,.,.,},}}}}...}||....))|}}.||{{,....||,||......{{||...|||{|{{{{,.,..,,}}|}...,||....))}},.||{{{...,||{||......{{{{,..((({{{{{(.......})))...,}}....))}},.,{{{{...,||,((......,{{{...|||{{,,..,,,.,|,,|||,..,,,....|||||.,{{{,...,||.{{......,|||...|||||.....,,..||||||,...,,....|||||..........}((((.......}}}}..|||||.........{{{.|||.........|||||..,,{,...,||.((..,,,..,,,...|||{{.,..,,,..|{{.||,......(((((....))))).....((((.......))))..)))}}.....,,..))).))).........)))))..........{.{(((.....))))}...,,...{|||||...||,.||{,....)),))..,,,....,|||||,........(({{...))}}..,,,,,.}||}}...,,.,,.)))))..,,,,,.))))))...)))))..,........}}))).....))))).,))))),,.,.......}|(((({({.{{{{...{{{{{{.,,..{{.....|,,}}|...}).})))....)).)).}))))),.((((((((........)))))))).....................))),.)))}}}))).
Transcripts
| ID | Sequence | Length | GC Content |
|---|---|---|---|
| NM_001394862.1 | AGCACAGAGUUGGGAGUGACUCCAGAGCCUCCAGCAAGAUGCUACUGAU… | 1227 nt | 0.5860 |
| NM_006249.5 | AGCACAGAGUUGGGAGUGACUCCAGAGCCUCCAGCAAGAUGCUACUGAU… | 1101 nt | 0.5822 |
Summary
This gene encodes a member of the heterogeneous family of basic, proline-rich, human salivary glycoproteins. Multiple alleles of this gene exhibiting variations in the length of the tandem repeats have been identified. The reference genome encodes the "Long"" allele. The protein isoforms encoded by this gene are recognized as the ""first line of oral defense"" against the detrimental effects of polyphenols in the diet and pathogen infections. This gene is located in a cluster of closely related salivary proline-rich proteins on chromosome 12. [provided by RefSeq
Forensic Context
Nov 2015]"
Genomic Tracks
